The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice - PubMed (original) (raw)

Metabolome-wide association study on ABCA7 indicates a role of ceramide metabolism in Alzheimer's disease.

Dehghan A, Pinto RC, Karaman I, Huang J, Durainayagam BR, Ghanbari M, Nazeer A, Zhong Q, Liggi S, Whiley L, Mustafa R, Kivipelto M, Solomon A, Ngandu T, Kanekiyo T, Aikawa T, Radulescu CI, Barnes SJ, Graça G, Chekmeneva E, Camuzeaux S, Lewis MR, Kaluarachchi MR, Ikram MA, Holmes E, Tzoulaki I, Matthews PM, Griffin JL, Elliott P. Dehghan A, et al. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2206083119. doi: 10.1073/pnas.2206083119. Epub 2022 Oct 21. Proc Natl Acad Sci U S A. 2022. PMID: 36269859 Free PMC article.