Distinct neural correlates of visual long-term memory for spatial location and object identity: a positron emission tomography study in humans - PubMed (original) (raw)

Comparative Study

Distinct neural correlates of visual long-term memory for spatial location and object identity: a positron emission tomography study in humans

C Moscovitch et al. Proc Natl Acad Sci U S A. 1995.

Abstract

The purpose of the present study was to investigate by using positron emission tomography (PET) whether the cortical pathways that are involved in visual perception of spatial location and object identity are also differentially implicated in retrieval of these types of information from episodic long-term memory. Subjects studied a set of displays consisting of three unique representational line drawings arranged in different spatial configurations. Later, while undergoing PET scanning, subjects' memory for spatial location and identity of the objects in the displays was tested and compared to a perceptual baseline task involving the same displays. In comparison to the baseline task, each of the memory tasks activated both the dorsal and the ventral pathways in the right hemisphere but not to an equal extent. There was also activation of the right prefrontal cortex. When PET scans of the memory tasks were compared to each other, areas of activation were very circumscribed and restricted to the right hemisphere: For retrieval of object identity, the area was in the inferior temporal cortex in the region of the fusiform gyrus (area 37), whereas for retrieval of spatial location, it was in the inferior parietal lobule in the region of the supramarginal gyrus (area 40). Thus, our study shows that distinct neural pathways are activated during retrieval of information about spatial location and object identity from long-term memory.

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References

1. Proc Natl Acad Sci U S A. 1994 Mar 15;91(6):2016-20 - PubMed
1. Nature. 1993 Jun 17;363(6430):623-5 - PubMed
1. Neuropsychologia. 1981;19(6):781-93 - PubMed
1. Nature. 1994 Apr 14;368(6472):633-5 - PubMed
1. Eur J Neurosci. 1992;4(2):154-165 - PubMed

Distinct neural correlates of visual long-term memory for spatial location and object identity: a positron emission tomography study in humans - PubMed (original) (raw)