Serum levels of interleukin 6 in patients with lung cancer - PubMed (original) (raw)
Serum levels of interleukin 6 in patients with lung cancer
H Yanagawa et al. Br J Cancer. 1995 May.
Free PMC article
Abstract
Serum interleukin 6 (IL-6) levels were measured in 75 patients with lung cancer and in 20 patients with benign lung diseases. IL-6 was detectable in 29 patients with lung cancer (39%), but was not detectable in any of the patients with benign lung diseases. Serum C-reactive protein levels and plasma fibrinogen levels were significantly higher and serum albumin concentration was significantly lower in lung cancer patients with detectable serum IL-6 levels than in those without detectable serum IL-6 levels and in patients with benign lung diseases. On the other hand, no significant difference was observed in blood platelet counts in these three groups. Moreover, serum IL-6 levels were not significantly different in lung cancer patients with or without clinically demonstrated distant metastasis. These results suggest that IL-6 may be a mediator of various reactions including an inflammatory response in lung cancer patients.
References
- Lancet. 1987 Oct 17;2(8564):921 - PubMed
- Eur J Immunol. 1986 Aug;16(8):1017-9 - PubMed
- Nature. 1988 Mar 3;332(6159):83-5 - PubMed
- Arthritis Rheum. 1988 Jun;31(6):784-8 - PubMed
- Eur J Immunol. 1988 Aug;18(8):1259-64 - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Research Materials