Postoperative delirium in the elderly - PubMed (original) (raw)
Review
Postoperative delirium in the elderly
S S Parikh et al. Anesth Analg. 1995 Jun.
Abstract
Postoperative delirium is common in the elderly in the postoperative period. It can result in increased morbidity, delayed functional recovery, and prolonged hospital stay. In surgical patients, factors such as age, alcohol abuse, low baseline cognition, severe metabolic derangement, hypoxia, hypotension, and type of surgery appear to contribute to postoperative delirium. Anesthetics, notably anticholinergic drugs and benzodiazepines, increase the risk for delirium. Despite the above recommendations, postoperative delirium in the elderly is poorly understood. Clearly, further studies are needed to determine the risk and long-term outcome of delirium in the elderly population. Research is also needed to define the effects of hypoxemia on cerebral function and whether oxygen therapy has any benefits. The geriatric-anesthesiologic intervention program of pre- and postoperative geriatric assessment, early surgery, thrombosis prophylaxis, oxygen therapy, prevention and treatment of perioperative decrease in blood pressure, and vigorous treatment of any postoperative complications showed some promise, but further definitive studies are needed.
Similar articles
- Postoperative delirium.
Cavaliere F, D'Ambrosio F, Volpe C, Masieri S. Cavaliere F, et al. Curr Drug Targets. 2005 Nov;6(7):807-14. doi: 10.2174/138945005774574489. Curr Drug Targets. 2005. PMID: 16305459 Review. - Postoperative Delirium after elective and emergency surgery: analysis and checking of risk factors. A study protocol.
Agnoletti V, Ansaloni L, Catena F, Chattat R, De Cataldis A, Di Nino G, Franceschi C, Gagliardi S, Melotti RM, Potalivo A, Taffurelli M. Agnoletti V, et al. BMC Surg. 2005 May 28;5:12. doi: 10.1186/1471-2482-5-12. BMC Surg. 2005. PMID: 15921527 Free PMC article. - Postoperative delirium.
Winawer N. Winawer N. Med Clin North Am. 2001 Sep;85(5):1229-39. doi: 10.1016/s0025-7125(05)70374-6. Med Clin North Am. 2001. PMID: 11565496 Review. - Risk factors contributing to postoperative delirium in geriatric patients postorthopedic surgery.
Wang J, Li Z, Yu Y, Li B, Shao G, Wang Q. Wang J, et al. Asia Pac Psychiatry. 2015 Dec;7(4):375-82. doi: 10.1111/appy.12193. Epub 2015 Jun 10. Asia Pac Psychiatry. 2015. PMID: 26097170 - [Postoperative cognitive dysfunction of older surgical patients].
Damuleviciene G, Lesauskaite V, Macijauskiene J. Damuleviciene G, et al. Medicina (Kaunas). 2010;46(3):169-75. Medicina (Kaunas). 2010. PMID: 20516755 Review. Lithuanian.
Cited by
- Impact of intraoperative hypotension and blood pressure fluctuations on early postoperative delirium after non-cardiac surgery.
Hirsch J, DePalma G, Tsai TT, Sands LP, Leung JM. Hirsch J, et al. Br J Anaesth. 2015 Sep;115(3):418-26. doi: 10.1093/bja/aeu458. Epub 2015 Jan 23. Br J Anaesth. 2015. PMID: 25616677 Free PMC article. - Anaesthesia in elderly patients with neurodegenerative disorders: special considerations.
Burton DA, Nicholson G, Hall GM. Burton DA, et al. Drugs Aging. 2004;21(4):229-42. doi: 10.2165/00002512-200421040-00002. Drugs Aging. 2004. PMID: 15012169 Review. - Delirium associated with buprenorphine use in cardiac surgery: A retrospective cohort study.
Selvaraj T, Thangavel P, Siddhaarth K. Selvaraj T, et al. Indian J Anaesth. 2022 Apr;66(4):266-271. doi: 10.4103/ija.ija_780_21. Epub 2022 Apr 20. Indian J Anaesth. 2022. PMID: 35663209 Free PMC article. - Metabolic Abnormalities of Erythrocytes as a Risk Factor for Alzheimer's Disease.
Kosenko EA, Tikhonova LA, Montoliu C, Barreto GE, Aliev G, Kaminsky YG. Kosenko EA, et al. Front Neurosci. 2018 Jan 5;11:728. doi: 10.3389/fnins.2017.00728. eCollection 2017. Front Neurosci. 2018. PMID: 29354027 Free PMC article. Review. - A history of aggression is a risk factor for postoperative confusion in elderly male drinkers.
Kudoh A, Takase H, Matsuno S, Katagai H. Kudoh A, et al. J Anesth. 2007;21(1):13-8. doi: 10.1007/s00540-006-0454-1. Epub 2007 Jan 30. J Anesth. 2007. PMID: 17285407
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical