[Mechanism of scavenging effects of (-)-epigallocatechin gallate on active oxygen free radicals] - PubMed (original) (raw)
[Article in Chinese]
Affiliations
- PMID: 7801780
Free article
[Mechanism of scavenging effects of (-)-epigallocatechin gallate on active oxygen free radicals]
[Article in Chinese]
X Q Yang et al. Zhongguo Yao Li Xue Bao. 1994 Jul.
Free article
Abstract
The concentration of 50% scavenging ratio (SC50) and the scavenging rate constants (k) and stiochiometric factor (n) were determined when (-)-epigallocatechin gallate [(-)-EGCG] scavenging superoxide anion free radical (O2.-) and hydroxyl radical (.OH). The mechanism of scavenging active free radicals of (-)-EGCG and the promotion of (-)-EGCG free radical and its structure were analyzed in vitro. Our results suggest that the centers of scavenging reaction of (-)-EGCG are B, D, and A cycles, and each (-)-EGCG traps six O2.- or .OH. It is in accord with the value of stiochiometric factor n = 6.
Similar articles
- Scavenging effects of tetramethylpyrazine on active oxygen free radicals.
Zhang ZH, Yu SZ, Wang ZT, Zhao BL, Hou JW, Yang FJ, Xin WJ. Zhang ZH, et al. Zhongguo Yao Li Xue Bao. 1994 May;15(3):229-31. Zhongguo Yao Li Xue Bao. 1994. PMID: 7976377 - Production of hydrogen peroxide and methionine sulfoxide by epigallocatechin gallate and antioxidants.
Sakagami H, Arakawa H, Maeda M, Satoh K, Kadofuku T, Fukuchi K, Gomi K. Sakagami H, et al. Anticancer Res. 2001 Jul-Aug;21(4A):2633-41. Anticancer Res. 2001. PMID: 11724332 - Stopped-flow kinetic study of the aroxyl radical-scavenging action of catechins and vitamin C in ethanol and micellar solutions.
Mitani S, Ouchi A, Watanabe E, Kanesaki Y, Nagaoka S, Mukai K. Mitani S, et al. J Agric Food Chem. 2008 Jun 25;56(12):4406-17. doi: 10.1021/jf703770m. Epub 2008 May 24. J Agric Food Chem. 2008. PMID: 18500808 - Free radicals and their scavenging in stroke.
Belch JJ. Belch JJ. Scott Med J. 1992 Jun;37(3):67-8. doi: 10.1177/003693309203700301. Scott Med J. 1992. PMID: 1496354 Review. No abstract available.
Cited by
- Anti-infective properties of epigallocatechin-3-gallate (EGCG), a component of green tea.
Steinmann J, Buer J, Pietschmann T, Steinmann E. Steinmann J, et al. Br J Pharmacol. 2013 Mar;168(5):1059-73. doi: 10.1111/bph.12009. Br J Pharmacol. 2013. PMID: 23072320 Free PMC article. Review. - Antioxidant and antiviral activities of lipophilic epigallocatechin gallate (EGCG) derivatives.
Zhong Y, Ma CM, Shahidi F. Zhong Y, et al. J Funct Foods. 2012 Jan;4(1):87-93. doi: 10.1016/j.jff.2011.08.003. Epub 2011 Oct 4. J Funct Foods. 2012. PMID: 32288792 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources