A new class of DNA photolyases present in various organisms including aplacental mammals - PubMed (original) (raw)
Comparative Study
A new class of DNA photolyases present in various organisms including aplacental mammals
A Yasui et al. EMBO J. 1994.
Abstract
DNA photolyase specifically repairs UV light-induced cyclobutane-type pyrimidine dimers in DNA through a light-dependent reaction mechanism. We have obtained photolyase genes from Drosophila melanogaster (fruit fly), Oryzias latipes (killifish) and the marsupial Potorous tridactylis (rat kangaroo), the first photolyase gene cloned from a mammalian species. The deduced amino acid sequences of these higher eukaryote genes show only limited homology with microbial photolyase genes. Together with the previously cloned Carassius auratus (goldfish) gene they form a separate group of photolyase genes. A new classification for photolyases comprising two distantly related groups is proposed. For functional analysis P.tridactylis photolyase was expressed and purified as glutathione S-transferase fusion protein from Escherichia coli cells. The biologically active protein contained FAD as light-absorbing cofactor, a property in common with the microbial class photolyases. Furthermore, we found in the archaebacterium Methanobacterium thermoautotrophicum a gene similar to the higher eukaryote photolyase genes, but we could not obtain evidence for the presence of a homologous gene in the human genome. Our results suggest a divergence of photolyase genes in early evolution.
Similar articles
- Cloning of a marsupial DNA photolyase gene and the lack of related nucleotide sequences in placental mammals.
Kato T Jr, Todo T, Ayaki H, Ishizaki K, Morita T, Mitra S, Ikenaga M. Kato T Jr, et al. Nucleic Acids Res. 1994 Oct 11;22(20):4119-24. doi: 10.1093/nar/22.20.4119. Nucleic Acids Res. 1994. PMID: 7937136 Free PMC article. - Similarity among the Drosophila (6-4)photolyase, a human photolyase homolog, and the DNA photolyase-blue-light photoreceptor family.
Todo T, Ryo H, Yamamoto K, Toh H, Inui T, Ayaki H, Nomura T, Ikenaga M. Todo T, et al. Science. 1996 Apr 5;272(5258):109-12. doi: 10.1126/science.272.5258.109. Science. 1996. PMID: 8600518 - A putative blue-light receptor from Drosophila melanogaster.
Okano S, Kanno S, Takao M, Eker AP, Isono K, Tsukahara Y, Yasui A. Okano S, et al. Photochem Photobiol. 1999 Jan;69(1):108-13. doi: 10.1562/0031-8655(1999)069<0108:apblrf>2.3.co;2. Photochem Photobiol. 1999. PMID: 10063806 - DNA photorepair: chromophore composition and function in two classes of DNA photolyases.
Jorns MS. Jorns MS. Biofactors. 1990 Oct;2(4):207-11. Biofactors. 1990. PMID: 2282137 Review. - DNA repair by photolyases.
Kavakli IH, Ozturk N, Gul S. Kavakli IH, et al. Adv Protein Chem Struct Biol. 2019;115:1-19. doi: 10.1016/bs.apcsb.2018.10.003. Epub 2018 Dec 20. Adv Protein Chem Struct Biol. 2019. PMID: 30798929 Review.
Cited by
- Understanding Active Photoprotection: DNA-Repair Enzymes and Antioxidants.
Garcia-Mouronte E, Pérez-González LA, Naharro-Rodriguez J, Fernández Guarino M. Garcia-Mouronte E, et al. Life (Basel). 2024 Jun 28;14(7):822. doi: 10.3390/life14070822. Life (Basel). 2024. PMID: 39063576 Free PMC article. Review. - A recombinant fungal photolyase autonomously enters human cell nuclei to fix UV-induced DNA lesions.
Bao Y, Fang W. Bao Y, et al. Biotechnol Lett. 2024 Jun;46(3):459-467. doi: 10.1007/s10529-024-03474-3. Epub 2024 Mar 25. Biotechnol Lett. 2024. PMID: 38523200 - Poaceae plants transfer cyclobutane pyrimidine dimer photolyase to chloroplasts for ultraviolet-B resistance.
Otake M, Teranishi M, Komatsu C, Hara M, Yoshiyama KO, Hidema J. Otake M, et al. Plant Physiol. 2024 Apr 30;195(1):326-342. doi: 10.1093/plphys/kiae060. Plant Physiol. 2024. PMID: 38345835 Free PMC article. - The Registration Situation and Use of Mycopesticides in the World.
Jiang Y, Wang J. Jiang Y, et al. J Fungi (Basel). 2023 Sep 16;9(9):940. doi: 10.3390/jof9090940. J Fungi (Basel). 2023. PMID: 37755048 Free PMC article. Review. - Divergent roles of Rad4 and Rad23 homologs in Metarhizium robertsii's resistance to solar ultraviolet damage.
Zhang YL, Peng H, Zhang K, Ying SH, Feng MG. Zhang YL, et al. Appl Environ Microbiol. 2023 Sep 28;89(9):e0099423. doi: 10.1128/aem.00994-23. Epub 2023 Sep 1. Appl Environ Microbiol. 2023. PMID: 37655890 Free PMC article.
References
- Nucleic Acids Res. 1989 Jun 26;17(12):4731-44 - PubMed
- Nature. 1962 Apr 28;194:406 - PubMed
- J Bacteriol. 1989 Nov;171(11):6323-9 - PubMed
- Photochem Photobiol. 1989 Nov;50(5):633-7 - PubMed
- J Biol Chem. 1990 May 15;265(14):8009-15 - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases