Regulation of translation and cell growth by eIF-4E - PubMed (original) (raw)
Review
Regulation of translation and cell growth by eIF-4E
N Sonenberg. Biochimie. 1994.
Abstract
This review discusses the regulation of a key controlling step in the initiation of protein synthesis, the binding of mRNA to ribosomes. Particular focus is given to the phosphorylation of the cap-binding factor, eIF-4E, and the role of this factor in the regulation of cell growth.
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