Survival of the Q fever agent Coxiella burnetii in the phagolysosome - PubMed (original) (raw)
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Survival of the Q fever agent Coxiella burnetii in the phagolysosome
O G Baca et al. Trends Microbiol. 1994 Dec.
Abstract
The Q fever agent, Coxiella burnetii, thrives in the acidic environment of the phagolysosome of the host cell. How this obligate intracellular agent manages to survive within this hostile milieu is unknown; however, several of its enzymes may eliminate or prevent the formation of toxic oxygen metabolites by the host cell. Also implicated as virulence factors are its surface lipopolysaccharide and plasmids.
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