The neurobiology of somatostatin - PubMed (original) (raw)
Affiliations
- PMID: 7907281
Review
The neurobiology of somatostatin
J Epelbaum et al. Crit Rev Neurobiol. 1994.
Abstract
This review summarizes the recent findings on the localization of somatostatin (SRIF)-related peptides in local circuit interneurons and long projection neurons. These differential locations are discussed in relation to the multiple roles of SRIF 14 and SRIF 28 in neuroendocrine and autonomic regulation. The coexistence of SRIF with other neuropeptides and neurotransmitters, including nitric oxide, is described. The pharmacological and functional properties of the recently cloned family of SRIF receptor subtypes are reviewed as well as their localization. Finally, the decrease in SRIF concentrations in the cerebrospinal fluid (CSF) and the central nervous system (CNS) commonly associated with Alzheimer's disease is critically evaluated.
Similar articles
- Somatostatin, Alzheimer's disease and cognition: an old story coming of age?
Epelbaum J, Guillou JL, Gastambide F, Hoyer D, Duron E, Viollet C. Epelbaum J, et al. Prog Neurobiol. 2009 Oct;89(2):153-61. doi: 10.1016/j.pneurobio.2009.07.002. Epub 2009 Jul 10. Prog Neurobiol. 2009. PMID: 19595735 Review. - [Somatostatin: a ubiquitous peptide].
Epelbaum J, Dournaud P. Epelbaum J, et al. C R Seances Soc Biol Fil. 1998;192(4):597-606. C R Seances Soc Biol Fil. 1998. PMID: 9842466 Review. French. - Somatostatin and Alzheimer's disease.
Burgos-Ramos E, Hervás-Aguilar A, Aguado-Llera D, Puebla-Jiménez L, Hernández-Pinto AM, Barrios V, Arilla-Ferreiro E. Burgos-Ramos E, et al. Mol Cell Endocrinol. 2008 May 14;286(1-2):104-11. doi: 10.1016/j.mce.2008.01.014. Epub 2008 Feb 3. Mol Cell Endocrinol. 2008. PMID: 18359553 Review. - Characterization of cloned somatostatin receptors SSTR4 and SSTR5.
Raynor K, O'Carroll AM, Kong H, Yasuda K, Mahan LC, Bell GI, Reisine T. Raynor K, et al. Mol Pharmacol. 1993 Aug;44(2):385-92. Mol Pharmacol. 1993. PMID: 8102785 - Are somatostatin and cortistatin two siblings in regulating endocrine secretions? In vitro work ahead.
Gahete MD, Durán-Prado M, Luque RM, Martínez-Fuentes AJ, Vázquez-Martínez R, Malagón MM, Castaño JP. Gahete MD, et al. Mol Cell Endocrinol. 2008 May 14;286(1-2):128-34. doi: 10.1016/j.mce.2007.11.013. Epub 2007 Nov 22. Mol Cell Endocrinol. 2008. PMID: 18215456 Review.
Cited by
- Alterations in synapses and mitochondria induced by acute or chronic intermittent hypoxia in the pre-Bötzinger complex of rats: an ultrastructural triple-labeling study with immunocytochemistry and histochemistry.
Kang J, Lu N, Yang S, Guo B, Zhu Y, Wu S, Huang X, Wong-Riley MTT, Liu YY. Kang J, et al. Front Cell Neurosci. 2023 Jun 16;17:1132241. doi: 10.3389/fncel.2023.1132241. eCollection 2023. Front Cell Neurosci. 2023. PMID: 37396926 Free PMC article. - Class A and C GPCR Dimers in Neurodegenerative Diseases.
Caniceiro AB, Bueschbell B, Schiedel AC, Moreira IS. Caniceiro AB, et al. Curr Neuropharmacol. 2022;20(11):2081-2141. doi: 10.2174/1570159X20666220327221830. Curr Neuropharmacol. 2022. PMID: 35339177 Free PMC article. Review. - Somatostatin-Mediated Regulation of Retinoic Acid-Induced Differentiation of SH-SY5Y Cells: Neurotransmitters Phenotype Characterization.
Singh S, Somvanshi RK, Kumar U. Singh S, et al. Biomedicines. 2022 Feb 1;10(2):337. doi: 10.3390/biomedicines10020337. Biomedicines. 2022. PMID: 35203546 Free PMC article. - Review: Neuropathology findings in autonomic brain regions in SUDEP and future research directions.
Patodia S, Somani A, Thom M. Patodia S, et al. Auton Neurosci. 2021 Nov;235:102862. doi: 10.1016/j.autneu.2021.102862. Epub 2021 Jul 31. Auton Neurosci. 2021. PMID: 34411885 Free PMC article. Review. - Characterisation of medullary astrocytic populations in respiratory nuclei and alterations in sudden unexpected death in epilepsy.
Patodia S, Paradiso B, Ellis M, Somani A, Sisodiya SM, Devinsky O, Thom M. Patodia S, et al. Epilepsy Res. 2019 Nov;157:106213. doi: 10.1016/j.eplepsyres.2019.106213. Epub 2019 Oct 1. Epilepsy Res. 2019. PMID: 31610338 Free PMC article.