Small virus-like structure in fractions from scrapie hamster brain - PubMed (original) (raw)
Small virus-like structure in fractions from scrapie hamster brain
M Ozel et al. Lancet. 1994.
Abstract
The scrapie model in hamsters has been used to search for the agents that cause Creutzfeldt-Jakob disease in man and similar transmissible encephalopathies in animals. We found structures that are extraordinarily small for a virus, but exhibit viral structural properties in negatively stained samples, by electron microscopy in fractions containing scrapie-associated fibrils.
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