DNA-binding domains: targets for viral and cellular regulators - PubMed (original) (raw)
Review
DNA-binding domains: targets for viral and cellular regulators
S Wagner et al. Curr Opin Cell Biol. 1994 Jun.
Abstract
Specific DNA binding by eukaryotic transcription factors is conferred by several types of sequence motif. These domains have been extensively studied with regard to their precise interaction with DNA and the basis of sequence specificity. Evidence is accumulating that DNA-binding domains serve functions in addition to binding DNA: they are also targets of viral and cellular regulatory proteins.
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