Viral interactions with the host-cell cytoskeleton: the role of retroviral proteases - PubMed (original) (raw)

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Viral interactions with the host-cell cytoskeleton: the role of retroviral proteases

R B Luftig et al. Trends Microbiol. 1994 May.

Abstract

A surprisingly large number of animal viruses interact with cytoskeletal elements inside infected cells at different stages of replication. For example, a viral protease is activated during assembly of murine leukemia viruses at the cell surface, which causes both the morphological conversion of 'immature' to 'mature' particles and a drastic reduction of the actin stress fiber network.

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