Legionnaires' disease in human immunodeficiency virus-infected patients: eight cases and review - PubMed (original) (raw)
Review
Legionnaires' disease in human immunodeficiency virus-infected patients: eight cases and review
S P Blatt et al. Clin Infect Dis. 1994 Feb.
Abstract
Despite being a well-known pathogen for immunocompromised patients, Legionella pneumophila has infrequently been described in persons with infection due to human immunodeficiency virus (HIV). Since 1986, we have identified eight cases of legionella pneumonia among seven HIV-infected persons enrolled in the HIV Natural History Study of the U.S. Air Force. The median CD4+ T cell count for these patients was 83/mm3; 50% of the cases occurred in persons for whom AIDS was previously diagnosed, and five of the cases were nosocomial. Six of the patients had coexistent pulmonary infections. None of the cases occurred among persons receiving prophylactic therapy with trimethoprim-sulfamethoxazole. Therapeutically, all patients appeared to respond well to standard antilegionella therapy or high doses of trimethoprim-sulfamethoxazole. Overall, these seven patients represent 1.7% of the patients with late-stage HIV infection (Walter Reed stage 5 or 6) in this cohort. L. pneumophila, although remaining an uncommon pathogen for HIV-infected patients, may produce serious disease in this population. HIV-infected persons should be considered at risk for legionnaires' disease, particularly in institutions where potable water supplies have become contaminated.
Comment in
- Legionnaires' disease in patients infected with human immunodeficiency virus.
Gutiérrez Rodero F, Ortiz de la Tabla V, Martínez C, Masiá MM, Chiner E, Calpe JL. Gutiérrez Rodero F, et al. Clin Infect Dis. 1995 Sep;21(3):712-3. doi: 10.1093/clinids/21.3.712. Clin Infect Dis. 1995. PMID: 8527592 No abstract available.
Similar articles
- Legionella pneumonia and HIV: case reports and review of the literature.
Sandkovsky U, Sandkovsky G, Suh J, Smith B, Sharp V, Polsky B. Sandkovsky U, et al. AIDS Patient Care STDS. 2008 Jun;22(6):473-81. doi: 10.1089/apc.2007.0111. AIDS Patient Care STDS. 2008. PMID: 18462074 Review. - Culture proven Legionella pneumophila pneumonia in a HIV-infected patient: case report and review.
Franzin L, Dal Conte I, Cabodi D, Sinicco A. Franzin L, et al. J Infect. 2002 Oct;45(3):199-201. doi: 10.1016/s0163-4453(02)91030-3. J Infect. 2002. PMID: 12387779 Review. - [Pneumonia caused by Legionella pneumophila and acquired immunodeficiency syndrome].
Barbé J, Capdevila JA, García Quintana A, Ferrer A. Barbé J, et al. Enferm Infecc Microbiol Clin. 1992 Nov;10(9):561-2. Enferm Infecc Microbiol Clin. 1992. PMID: 1489805 Spanish. No abstract available. - Legionnaires' disease in patients infected with human immunodeficiency virus.
Gutiérrez Rodero F, Ortiz de la Tabla V, Martínez C, Masiá MM, Chiner E, Calpe JL. Gutiérrez Rodero F, et al. Clin Infect Dis. 1995 Sep;21(3):712-3. doi: 10.1093/clinids/21.3.712. Clin Infect Dis. 1995. PMID: 8527592 No abstract available. - Legionella pneumonia and HIV infection: a case report.
Stroup JS, Hendrickson SE, Neil M. Stroup JS, et al. AIDS Read. 2004 May;14(5):267-70. AIDS Read. 2004. PMID: 15199856
Cited by
- Legionnaires' Disease Complicated with Rhabdomyolysis and Acute Kidney Injury in an AIDS Patient.
Seegobin K, Maharaj S, Baldeo C, Downes JP, Reddy P. Seegobin K, et al. Case Rep Infect Dis. 2017;2017:8051096. doi: 10.1155/2017/8051096. Epub 2017 Oct 4. Case Rep Infect Dis. 2017. PMID: 29109879 Free PMC article. - Atypical bacterial pneumonia in the HIV-infected population.
Head BM, Trajtman A, Rueda ZV, Vélez L, Keynan Y. Head BM, et al. Pneumonia (Nathan). 2017 Aug 25;9:12. doi: 10.1186/s41479-017-0036-z. eCollection 2017. Pneumonia (Nathan). 2017. PMID: 28856082 Free PMC article. Review. - Legionella pneumophila serogroup 4 isolated from joint tissue.
Linscott AJ, Poulter MD, Ward K, Bruckner DA. Linscott AJ, et al. J Clin Microbiol. 2004 Mar;42(3):1365-6. doi: 10.1128/JCM.42.3.1365-1366.2004. J Clin Microbiol. 2004. PMID: 15004121 Free PMC article. - Legionella and Legionnaires' disease: 25 years of investigation.
Fields BS, Benson RF, Besser RE. Fields BS, et al. Clin Microbiol Rev. 2002 Jul;15(3):506-26. doi: 10.1128/CMR.15.3.506-526.2002. Clin Microbiol Rev. 2002. PMID: 12097254 Free PMC article. Review. - Impact of the human immunodeficiency virus epidemic on detection of Mycobacterium isolates in a general hospital.
Bouza E, Albadalejo J, Cercenado E, Ruiz Serrano MJ, Vicente T, Ortega A. Bouza E, et al. J Clin Microbiol. 1997 Apr;35(4):1013-5. doi: 10.1128/jcm.35.4.1013-1015.1997. J Clin Microbiol. 1997. PMID: 9157121 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
Research Materials