Mechanisms of virus uncoating - PubMed (original) (raw)
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Mechanisms of virus uncoating
U F Greber et al. Trends Microbiol. 1994 Feb.
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Abstract
In a virus particle, the genome is highly condensed and protected by proteins and membrane bilayers. Before it can be replicated in a new host cell, uncoating must take place. Recent studies on enveloped and nonenveloped animal viruses indicate that uncoating occurs through complex, multistep processes triggered by virus-host-cell interactions.
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