Synthetic enhancement in gene interaction: a genetic tool come of age - PubMed (original) (raw)

Review

Synthetic enhancement in gene interaction: a genetic tool come of age

L Guarente. Trends Genet. 1993 Oct.

Abstract

Synthetic enhancement, in which one mutation exacerbates the severity of another, is a genetic interaction of increasing importance in biology. This review focuses on the logic of interpreting synthetic enhancement, and begins by comparing the phenomenon with genetic suppression.

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