Covariations between hippocampal mossy fibres and working and reference memory in spatial and non-spatial radial maze tasks in mice - PubMed (original) (raw)
Comparative Study
Covariations between hippocampal mossy fibres and working and reference memory in spatial and non-spatial radial maze tasks in mice
W E Crusio et al. Eur J Neurosci. 1993.
Abstract
Male mice from nine inbred mouse strains were tested at the age of 3 months in either a spatial or a non-spatial version of the radial maze. Only four out of eight arms contained food rewards, permitting simultaneous assessment of working and reference memory in both situations. Other animals from the same strains were processed histologically to estimate the strain-specific extents of the mossy fibre projections. No significant between-task correlations were obtained for either working or reference memory. However, measures of working and reference memory correlated with each other within tasks. This suggests that these concepts may perhaps not be validly used in the mouse. Large, positive correlations of the size of the intra- and infrapyramidal mossy fibre projection with both working and reference memory were obtained in the spatial radial maze task, but not in the non-spatial one. We conclude that heritable variations of the hippocampal intra- and infrapyramidal mossy fibre projection influence processes related to spatial learning capabilities in radial mazes.
Similar articles
- Hippocampal mossy fibers and radial-maze learning in the mouse: a correlation with spatial working memory but not with non-spatial reference memory.
Schwegler H, Crusio WE, Brust I. Schwegler H, et al. Neuroscience. 1990;34(2):293-8. doi: 10.1016/0306-4522(90)90139-u. Neuroscience. 1990. PMID: 2333144 - No correlations between spatial and non-spatial reference memory in a T-maze task and hippocampal mossy fibre distribution in the mouse.
Crusio WE, Bertholet JY, Schwegler H. Crusio WE, et al. Behav Brain Res. 1990 Dec 21;41(3):251-9. doi: 10.1016/0166-4328(90)90112-r. Behav Brain Res. 1990. PMID: 2288676 - Genetic variation in the morphology of the septo-hippocampal cholinergic and GABAergic systems in mice: II. Morpho-behavioral correlations.
Schwegler H, Boldyreva M, Linke R, Wu J, Zilles K, Crusio WE. Schwegler H, et al. Hippocampus. 1996;6(5):535-45. doi: 10.1002/(SICI)1098-1063(1996)6:5<535::AID-HIPO6>3.0.CO;2-H. Hippocampus. 1996. PMID: 8953306 - Correlations between radial-maze learning and structural variations of septum and hippocampus in rodents.
Schwegler H, Crusio WE. Schwegler H, et al. Behav Brain Res. 1995 Feb;67(1):29-41. doi: 10.1016/0166-4328(95)91998-3. Behav Brain Res. 1995. PMID: 7748498 Review. - Spatial learning in the 5-HT1B receptor knockout mouse: selective facilitation/impairment depending on the cognitive demand.
Buhot MC, Wolff M, Benhassine N, Costet P, Hen R, Segu L. Buhot MC, et al. Learn Mem. 2003 Nov-Dec;10(6):466-77. doi: 10.1101/lm.60203. Learn Mem. 2003. PMID: 14657258 Review.
Cited by
- Exercising New Neurons to Vanquish Alzheimer Disease.
Llorens-Martín M. Llorens-Martín M. Brain Plast. 2018 Dec 12;4(1):111-126. doi: 10.3233/BPL-180065. Brain Plast. 2018. PMID: 30564550 Free PMC article. Review. - New functions of Semaphorin 3E and its receptor PlexinD1 during developing and adult hippocampal formation.
Mata A, Gil V, Pérez-Clausell J, Dasilva M, González-Calixto MC, Soriano E, García-Verdugo JM, Sanchez-Vives MV, Del Río JA. Mata A, et al. Sci Rep. 2018 Jan 22;8(1):1381. doi: 10.1038/s41598-018-19794-0. Sci Rep. 2018. PMID: 29358640 Free PMC article. - Learning spatial orientation tasks in the radial-maze and structural variation in the hippocampus in inbred mice.
Crusio WE, Schwegler H. Crusio WE, et al. Behav Brain Funct. 2005 Apr 22;1(1):3. doi: 10.1186/1744-9081-1-3. Behav Brain Funct. 2005. PMID: 15916698 Free PMC article. - Hippocampal morphology in the inbred mouse strains NZB and CBA/H and their reciprocal congenics for the nonpseudoautosomal region of the Y chromosome.
Guillot PV, Sluyter F, Laghmouch A, Roubertoux PL, Crusio WE. Guillot PV, et al. Behav Genet. 1996 Jan;26(1):1-5. doi: 10.1007/BF02361153. Behav Genet. 1996. PMID: 8852726 - Converging models of schizophrenia--Network alterations of prefrontal cortex underlying cognitive impairments.
Sakurai T, Gamo NJ, Hikida T, Kim SH, Murai T, Tomoda T, Sawa A. Sakurai T, et al. Prog Neurobiol. 2015 Nov;134:178-201. doi: 10.1016/j.pneurobio.2015.09.010. Epub 2015 Sep 25. Prog Neurobiol. 2015. PMID: 26408506 Free PMC article. Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
Molecular Biology Databases