cDNA cloning and chromosomal mapping of human N-acetylglucosaminyltransferase V+ - PubMed (original) (raw)
Comparative Study
. 1994 Jan 14;198(1):318-27.
doi: 10.1006/bbrc.1994.1045.
Affiliations
- PMID: 8292036
- DOI: 10.1006/bbrc.1994.1045
Comparative Study
cDNA cloning and chromosomal mapping of human N-acetylglucosaminyltransferase V+
H Saito et al. Biochem Biophys Res Commun. 1994.
Abstract
Human N-acetylglucosaminyltransferase V (GnT-V, EC 2.4.1.155) cDNA was isolated from a human fetal liver cDNA library. Oligonucleotide primers for polymerase chain reaction were designed according to the amino acid sequence of human GnT-V. Screening for the cDNA was carried out by plaque hybridization using PCR products of about 500 bp. Human GnT-V has 741 amino acids and six putative N-glycosylation sites. The homology to rat GnT-V is 88% at the nucleotide level and is 97% at the amino acid level, and there is one amino acid insertion. Using the cDNA clones as probe, five overlapping genomic clones have been isolated from a human phagemid DNA library. The GnT-V gene has been mapped to chromosome 2q21 using fluorescence in situ hybridization.
Similar articles
- cDNA cloning, expression, and chromosomal localization of human N-acetylglucosaminyltransferase III (GnT-III).
Ihara Y, Nishikawa A, Tohma T, Soejima H, Niikawa N, Taniguchi N. Ihara Y, et al. J Biochem. 1993 Jun;113(6):692-8. doi: 10.1093/oxfordjournals.jbchem.a124105. J Biochem. 1993. PMID: 8370666 - Molecular cloning and expression of cDNA encoding the rat UDP-N-acetylglucosamine:alpha-6-D-mannoside beta-1,2-N-acetylglucosaminyltransferase II.
D'Agostaro GA, Zingoni A, Moritz RL, Simpson RJ, Schachter H, Bendiak B. D'Agostaro GA, et al. J Biol Chem. 1995 Jun 23;270(25):15211-21. doi: 10.1074/jbc.270.25.15211. J Biol Chem. 1995. PMID: 7797505 - A novel second isoenzyme of the human UDP-N-acetylglucosamine:alpha1,3-D-mannoside beta1,4-N-acetylglucosaminyltransferase family: cDNA cloning, expression, and chromosomal assignment.
Yoshida A, Minowa MT, Takamatsu S, Hara T, Ikenaga H, Takeuchi M. Yoshida A, et al. Glycoconj J. 1998 Dec;15(12):1115-23. doi: 10.1023/a:1006951519522. Glycoconj J. 1998. PMID: 10372966 - Tissue specific expression and chromosomal mapping of a human UDP-N-acetylglucosamine: alpha1,3-d-mannoside beta1, 4-N-acetylglucosaminyltransferase.
Yoshida A, Minowa MT, Takamatsu S, Hara T, Oguri S, Ikenaga H, Takeuchi M. Yoshida A, et al. Glycobiology. 1999 Mar;9(3):303-10. doi: 10.1093/glycob/9.3.303. Glycobiology. 1999. PMID: 10024668 - Recent progress in the molecular biology of the cloned N-acetylglucosaminyltransferases.
Taniguchi N, Ihara Y. Taniguchi N, et al. Glycoconj J. 1995 Dec;12(6):733-8. doi: 10.1007/BF00731232. Glycoconj J. 1995. PMID: 8748148 Review.
Cited by
- Identification of Poly-N-Acetyllactosamine-Carrying Glycoproteins from HL-60 Human Promyelocytic Leukemia Cells Using a Site-Specific Glycome Analysis Method, Glyco-RIDGE.
Togayachi A, Tomioka A, Fujita M, Sukegawa M, Noro E, Takakura D, Miyazaki M, Shikanai T, Narimatsu H, Kaji H. Togayachi A, et al. J Am Soc Mass Spectrom. 2018 Jun;29(6):1138-1152. doi: 10.1007/s13361-018-1938-6. Epub 2018 Apr 19. J Am Soc Mass Spectrom. 2018. PMID: 29675740 Free PMC article. - Evolution of protein N-glycosylation process in Golgi apparatus which shapes diversity of protein N-glycan structures in plants, animals and fungi.
Wang P, Wang H, Gai J, Tian X, Zhang X, Lv Y, Jian Y. Wang P, et al. Sci Rep. 2017 Jan 11;7:40301. doi: 10.1038/srep40301. Sci Rep. 2017. PMID: 28074929 Free PMC article. - O-mannosylation and N-glycosylation: two coordinated mechanisms regulating the tumour suppressor functions of E-cadherin in cancer.
Carvalho S, Oliveira T, Bartels MF, Miyoshi E, Pierce M, Taniguchi N, Carneiro F, Seruca R, Reis CA, Strahl S, Pinho SS. Carvalho S, et al. Oncotarget. 2016 Oct 4;7(40):65231-65246. doi: 10.18632/oncotarget.11245. Oncotarget. 2016. PMID: 27533452 Free PMC article. - N-acetylglucosaminyltransferase IVa regulates metastatic potential of mouse hepatocarcinoma cells through glycosylation of CD147.
Fan J, Wang S, Yu S, He J, Zheng W, Zhang J. Fan J, et al. Glycoconj J. 2012 Aug;29(5-6):323-34. doi: 10.1007/s10719-012-9414-1. Epub 2012 Jun 27. Glycoconj J. 2012. PMID: 22736280 - Enhanced epithelial-mesenchymal transition-like phenotype in N-acetylglucosaminyltransferase V transgenic mouse skin promotes wound healing.
Terao M, Ishikawa A, Nakahara S, Kimura A, Kato A, Moriwaki K, Kamada Y, Murota H, Taniguchi N, Katayama I, Miyoshi E. Terao M, et al. J Biol Chem. 2011 Aug 12;286(32):28303-11. doi: 10.1074/jbc.M111.220376. Epub 2011 Jun 22. J Biol Chem. 2011. PMID: 21697088 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases