Vegetables, fruit, and colon cancer in the Iowa Women's Health Study - PubMed (original) (raw)

Vegetables, fruit, and colon cancer in the Iowa Women's Health Study

K A Steinmetz et al. Am J Epidemiol. 1994.

Abstract

Previous epidemiologic studies have shown an inverse association between vegetable and fruit consumption and colon cancer risk; few of these studies have been prospective or have focused on women. This report describes results from a prospective cohort study of 41,837 women aged 55-69 years who completed a 127-item food frequency questionnaire in 1986 and were monitored for cancer incidence for 5 years via the State Health Registry of Iowa. After specific exclusion criteria were applied, 212 colon cancer cases and 167,447 person-years were available for analysis. Intakes of 15 vegetable and fruit groups and dietary fiber were the major factors of interest. Consumption of garlic was inversely associated with risk, with an age- and energy-adjusted relative risk of 0.68 (95% confidence interval (CI) 0.46-1.02) for the uppermost versus the lowermost consumption levels. Inverse associations were also observed for intakes of all vegetables and dietary fiber; age- and energy-adjusted relative risks for the uppermost versus the lowermost intake quartiles were 0.73 (95% CI 0.47-1.13) and 0.80 (95% CI 0.49-1.31), respectively. Associations for the other vegetable and fruit groups were less remarkable.

PubMed Disclaimer

Comment in

• Re: "Vegetables, fruit, and colon cancer in the Iowa Women's Health Study".
  Cobb JE, Kang Y, Killian TE. Cobb JE, et al. Am J Epidemiol. 1995 Jun 1;141(11):1107. doi: 10.1093/oxfordjournals.aje.a117376. Am J Epidemiol. 1995. PMID: 7771445 No abstract available.
• Re: "Vegetables, fruit, and colon cancer in the Iowa Women's Health Study".
  Ballard-Barbash R, Krebs-Smith S, Subar AF. Ballard-Barbash R, et al. Am J Epidemiol. 1995 Jan 1;141(1):84-6. doi: 10.1093/oxfordjournals.aje.a117351. Am J Epidemiol. 1995. PMID: 7801971 No abstract available.

Similar articles

• Vegetables, fruit, and lung cancer in the Iowa Women's Health Study.
  Steinmetz KA, Potter JD, Folsom AR. Steinmetz KA, et al. Cancer Res. 1993 Feb 1;53(3):536-43. Cancer Res. 1993. PMID: 8425185
• Vegetable and fruit consumption and risks of colon and rectal cancer in a prospective cohort study: The Netherlands Cohort Study on Diet and Cancer.
  Voorrips LE, Goldbohm RA, van Poppel G, Sturmans F, Hermus RJ, van den Brandt PA. Voorrips LE, et al. Am J Epidemiol. 2000 Dec 1;152(11):1081-92. doi: 10.1093/aje/152.11.1081. Am J Epidemiol. 2000. PMID: 11117618
• Food-group consumption and colon cancer in the Adelaide Case-Control Study. I. Vegetables and fruit.
  Steinmetz KA, Potter JD. Steinmetz KA, et al. Int J Cancer. 1993 Mar 12;53(5):711-9. doi: 10.1002/ijc.2910530502. Int J Cancer. 1993. PMID: 8449594
• Relation of calcium, vitamin D, and dairy food intake to incidence of colon cancer among older women. The Iowa Women's Health Study.
  Bostick RM, Potter JD, Sellers TA, McKenzie DR, Kushi LH, Folsom AR. Bostick RM, et al. Am J Epidemiol. 1993 Jun 15;137(12):1302-17. doi: 10.1093/oxfordjournals.aje.a116640. Am J Epidemiol. 1993. PMID: 8333412 Review.
• Nutrition and colon cancer prevention.
  Bostick RM. Bostick RM. Nestle Nutr Workshop Ser Clin Perform Programme. 2000;4:67-85; discussion 85-6. doi: 10.1159/000061826. Nestle Nutr Workshop Ser Clin Perform Programme. 2000. PMID: 11490583 Review. No abstract available.

Cited by

• Potato Consumption and Risk of Site-Specific Cancers in Adults: A Systematic Review and Dose-Response Meta-Analysis of Observational Studies.
  Darooghegi Mofrad M, Mozaffari H, Askari MR, Amini MR, Jafari A, Surkan PJ, Azadbakht L. Darooghegi Mofrad M, et al. Adv Nutr. 2021 Oct 1;12(5):1705-1722. doi: 10.1093/advances/nmab024. Adv Nutr. 2021. PMID: 33861304 Free PMC article.
• Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis.
  Higdon JV, Delage B, Williams DE, Dashwood RH. Higdon JV, et al. Pharmacol Res. 2007 Mar;55(3):224-36. doi: 10.1016/j.phrs.2007.01.009. Epub 2007 Jan 25. Pharmacol Res. 2007. PMID: 17317210 Free PMC article. Review.
• Isothiocyanate exposure, glutathione S-transferase polymorphisms, and colorectal cancer risk.
  Yang G, Gao YT, Shu XO, Cai Q, Li GL, Li HL, Ji BT, Rothman N, Dyba M, Xiang YB, Chung FL, Chow WH, Zheng W. Yang G, et al. Am J Clin Nutr. 2010 Mar;91(3):704-11. doi: 10.3945/ajcn.2009.28683. Epub 2009 Dec 30. Am J Clin Nutr. 2010. PMID: 20042523 Free PMC article.
• Association of vegetable, fruit, and grain intakes with colorectal cancer: the Multiethnic Cohort Study.
  Nomura AM, Wilkens LR, Murphy SP, Hankin JH, Henderson BE, Pike MC, Kolonel LN. Nomura AM, et al. Am J Clin Nutr. 2008 Sep;88(3):730-7. doi: 10.1093/ajcn/88.3.730. Am J Clin Nutr. 2008. PMID: 18779290 Free PMC article.
• Role of traditional Islamic and Arabic plants in cancer therapy.
  Ahmad R, Ahmad N, Naqvi AA, Shehzad A, Al-Ghamdi MS. Ahmad R, et al. J Tradit Complement Med. 2016 May 21;7(2):195-204. doi: 10.1016/j.jtcme.2016.05.002. eCollection 2017 Apr. J Tradit Complement Med. 2016. PMID: 28417090 Free PMC article. Review.

Publication types

MeSH terms

LinkOut - more resources

• Full Text Sources

  • Silverchair Information Systems