Neurotrophins and their receptors--current concepts and implications for neurologic disease - PubMed (original) (raw)
Review
. 1993 Jun;121(2):200-14.
doi: 10.1006/exnr.1993.1087.
Affiliations
- PMID: 8339771
- DOI: 10.1006/exnr.1993.1087
Review
Neurotrophins and their receptors--current concepts and implications for neurologic disease
F F Eide et al. Exp Neurol. 1993 Jun.
Abstract
Nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 are members of a family of proteins (the neurotrophins) that promote the differentiation, growth, and survival of peripheral and central nervous system neurons. Recently, the trk family of proto-oncogenes has been found to encode signal-transducing receptors for these growth factors. This discovery has important implications for our understanding of the normal function of these factors in the developing and adult nervous system. In this review, we highlight recent advances in neurotrophin research and discuss their relevance to neurologic disease.
Similar articles
- Other neurotrophic factors: glial cell line-derived neurotrophic factor (GDNF).
Saarma M, Sariola H. Saarma M, et al. Microsc Res Tech. 1999 May 15-Jun 1;45(4-5):292-302. doi: 10.1002/(SICI)1097-0029(19990515/01)45:4/5<292::AID-JEMT13>3.0.CO;2-8. Microsc Res Tech. 1999. PMID: 10383122 Review. - Promoting neurotrophic effects by GPCR ligands.
Jeanneteau F, Chao MV. Jeanneteau F, et al. Novartis Found Symp. 2006;276:181-9; discussion 189-92, 233-7, 275-81. Novartis Found Symp. 2006. PMID: 16805430 Review. - Anterograde transport of neurotrophins and axodendritic transfer in the developing visual system.
von Bartheld CS, Byers MR, Williams R, Bothwell M. von Bartheld CS, et al. Nature. 1996 Feb 29;379(6568):830-3. doi: 10.1038/379830a0. Nature. 1996. PMID: 8587607 - Advances in small molecules promoting neurotrophic function.
Price RD, Milne SA, Sharkey J, Matsuoka N. Price RD, et al. Pharmacol Ther. 2007 Aug;115(2):292-306. doi: 10.1016/j.pharmthera.2007.03.005. Epub 2007 Apr 20. Pharmacol Ther. 2007. PMID: 17599430 Review. - [Neurotrophins. I: Molecular features].
Zazpe A, Del Río J. Zazpe A, et al. Rev Med Univ Navarra. 1997 Jul-Sep;41(3):173-9. Rev Med Univ Navarra. 1997. PMID: 10420923 Review. Spanish.
Cited by
- Differential contribution of TrkB and p75NTR to BDNF-dependent self-renewal, proliferation, and differentiation of adult neural stem cells.
Lozano-Ureña A, Frade JM. Lozano-Ureña A, et al. Front Mol Neurosci. 2023 Dec 22;16:1271820. doi: 10.3389/fnmol.2023.1271820. eCollection 2023. Front Mol Neurosci. 2023. PMID: 38188197 Free PMC article. - Association between Brain-Derived Neurotrophic Factor (BDNF) Levels in 2nd Trimester Amniotic Fluid and Fetal Development.
Antonakopoulos N, Iliodromiti Z, Mastorakos G, Iavazzo C, Valsamakis G, Salakos N, Papageorghiou A, Margeli A, Kalantaridou S, Creatsas G, Deligeoroglou E, Vrachnis N. Antonakopoulos N, et al. Mediators Inflamm. 2018 Dec 5;2018:8476217. doi: 10.1155/2018/8476217. eCollection 2018. Mediators Inflamm. 2018. PMID: 30622436 Free PMC article. - Neurotrophins role in depression neurobiology: a review of basic and clinical evidence.
Neto FL, Borges G, Torres-Sanchez S, Mico JA, Berrocoso E. Neto FL, et al. Curr Neuropharmacol. 2011 Dec;9(4):530-52. doi: 10.2174/157015911798376262. Curr Neuropharmacol. 2011. PMID: 22654714 Free PMC article. - Role of inflammation in bladder function and interstitial cystitis.
Grover S, Srivastava A, Lee R, Tewari AK, Te AE. Grover S, et al. Ther Adv Urol. 2011 Feb;3(1):19-33. doi: 10.1177/1756287211398255. Ther Adv Urol. 2011. PMID: 21789096 Free PMC article. - Exaggerated expression of inflammatory mediators in vasoactive intestinal polypeptide knockout (VIP-/-) mice with cyclophosphamide (CYP)-induced cystitis.
Girard BM, Malley SE, Braas KM, Waschek JA, May V, Vizzard MA. Girard BM, et al. J Mol Neurosci. 2008 Nov;36(1-3):188-99. doi: 10.1007/s12031-008-9084-4. Epub 2008 May 16. J Mol Neurosci. 2008. PMID: 18483878 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical