T cell mediated immunosuppression - PubMed (original) (raw)
Review
T cell mediated immunosuppression
D B Murphy. Curr Opin Immunol. 1993 Jun.
Abstract
Suppressor T cells down-regulate the activity of other cells in the immune system, and, albeit controversial, are believed to play a role in immunological tolerance and immunoregulation. Significant progress has been made in characterizing suppressor T cells and their receptors, and in elucidating mechanisms of immunosuppression. This knowledge is important for understanding the immune system and certain disease states and for favorably manipulating immunity.