Intake of potentially anticarcinogenic flavonoids and their determinants in adults in The Netherlands - PubMed (original) (raw)
Intake of potentially anticarcinogenic flavonoids and their determinants in adults in The Netherlands
M G Hertog et al. Nutr Cancer. 1993.
Abstract
Flavonoids are strong antioxidants that occur naturally in foods and can inhibit carcinogenesis in rodents. Accurate data on population-wide intakes of flavonoids are not available. Here, using data of the Dutch National Food Consumption Survey 1987-1988, we report the intake of the potentially anticarcinogenic flavonoids quercetin, kaempferol, myricetin, apigenin, and luteolin among 4,112 adults. The flavonoid content of vegetables, fruits, and beverages was determined by high-performance liquid chromatography. In all subjects, average intake of all flavonoids combined was 23 mg/day. The most important flavonoid was the flavonol quercetin (mean intake 16 mg/day). The most important sources of flavonoids were tea (48% of total intake), onions (29%), and apples (7%). Flavonoid intake did not vary between seasons; it was not correlated with total energy intake (r = 0.001), and it was only weakly correlated with the intake of vitamin A (retinol equivalents, r = 0.14), dietary fiber (r = 0.21), and vitamin C (r = 0.26). Our use of new analytic technology suggests that in the past flavonoid intake has been overestimated fivefold. However, on a milligram-per-day basis, the intake of the antioxidant flavonoids still exceeded that of the antioxidants beta-carotene and vitamin E. Thus flavonoids represent an important source of antioxidants in the human diet.
Similar articles
- Dietary flavonoids and cancer risk in the Zutphen Elderly Study.
Hertog MG, Feskens EJ, Hollman PC, Katan MB, Kromhout D. Hertog MG, et al. Nutr Cancer. 1994;22(2):175-84. doi: 10.1080/01635589409514342. Nutr Cancer. 1994. PMID: 14502846 - Dietary flavonoid sources in Australian adults.
Somerset SM, Johannot L. Somerset SM, et al. Nutr Cancer. 2008;60(4):442-9. doi: 10.1080/01635580802143836. Nutr Cancer. 2008. PMID: 18584477 - Flavonol and flavone intakes in US health professionals.
Sampson L, Rimm E, Hollman PC, de Vries JH, Katan MB. Sampson L, et al. J Am Diet Assoc. 2002 Oct;102(10):1414-20. doi: 10.1016/s0002-8223(02)90314-7. J Am Diet Assoc. 2002. PMID: 12396158 - Onions: a source of unique dietary flavonoids.
Slimestad R, Fossen T, Vågen IM. Slimestad R, et al. J Agric Food Chem. 2007 Dec 12;55(25):10067-80. doi: 10.1021/jf0712503. Epub 2007 Nov 13. J Agric Food Chem. 2007. PMID: 17997520 Review. - Health effects and bioavailability of dietary flavonols.
Hollman PC, Katan MB. Hollman PC, et al. Free Radic Res. 1999 Dec;31 Suppl:S75-80. doi: 10.1080/10715769900301351. Free Radic Res. 1999. PMID: 10694044 Review.
Cited by
- Polyphenol content and antioxidant activity of California almonds depend on cultivar and harvest year.
Bolling BW, Dolnikowski G, Blumberg JB, Chen CO. Bolling BW, et al. Food Chem. 2010 Oct 1;122(3):819-825. doi: 10.1016/j.foodchem.2010.03.068. Food Chem. 2010. PMID: 25544797 Free PMC article. - Effects on Liver Lipid Metabolism of the Naturally Occurring Dietary Flavone Luteolin-7-glucoside.
Sá C, Oliveira AR, Machado C, Azevedo M, Pereira-Wilson C. Sá C, et al. Evid Based Complement Alternat Med. 2015;2015:647832. doi: 10.1155/2015/647832. Epub 2015 May 31. Evid Based Complement Alternat Med. 2015. PMID: 26113868 Free PMC article. - Tissue-specific, development-dependent phenolic compounds accumulation profile and gene expression pattern in tea plant [Camellia sinensis].
Jiang X, Liu Y, Li W, Zhao L, Meng F, Wang Y, Tan H, Yang H, Wei C, Wan X, Gao L, Xia T. Jiang X, et al. PLoS One. 2013 Apr 30;8(4):e62315. doi: 10.1371/journal.pone.0062315. Print 2013. PLoS One. 2013. PMID: 23646127 Free PMC article. - Kaempferol - A dietary anticancer molecule with multiple mechanisms of action: Recent trends and advancements.
Kashyap D, Sharma A, Tuli HS, Sak K, Punia S, Mukherjee TK. Kashyap D, et al. J Funct Foods. 2017 Mar;30:203-219. doi: 10.1016/j.jff.2017.01.022. Epub 2017 Jan 18. J Funct Foods. 2017. PMID: 32288791 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous