Opsonization of Treponema pallidum is mediated by immunoglobulin G antibodies induced only by pathogenic treponemes - PubMed (original) (raw)

Opsonization of Treponema pallidum is mediated by immunoglobulin G antibodies induced only by pathogenic treponemes

J M Shaffer et al. Infect Immun. 1993 Feb.

Abstract

Rabbit antisera to Leptospira interrogans, Borrelia hermsii, and Treponema phagedenis biotype Reiter, reactive to shared spirochetal antigens, failed to enhance phagocytosis of Treponema pallidum by macrophages, while immunoglobulin G to Treponema pallidum subsp. pertenue and Treponema paraluiscuniculi promoted phagocytosis. Opsonic antibodies are directed to pathogen-restricted, not shared spirochetal, antigens.

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References

    1. J Bacteriol. 1991 Sep;173(17):5585-8 -PubMed
    1. Genitourin Med. 1990 Oct;66(5):367-73 -PubMed
    1. Infect Immun. 1992 Mar;60(3):1076-83 -PubMed
    1. Lancet. 1963 Feb 23;1(7278):423-5 -PubMed
    1. Br J Vener Dis. 1970 Dec;46(6):451-3 -PubMed

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