Differential expression of two genes encoding isoforms of the ATPase involved in sodium efflux in Saccharomyces cerevisiae - PubMed (original) (raw)

Comparative Study

. 1993 Jan;236(2-3):363-8.

doi: 10.1007/BF00277134.

Affiliations

• PMID: 8437581
• DOI: 10.1007/BF00277134

Comparative Study

Differential expression of two genes encoding isoforms of the ATPase involved in sodium efflux in Saccharomyces cerevisiae

B Garciadeblas et al. Mol Gen Genet. 1993 Jan.

Abstract

The ENA2 gene encoding a P-type ATPase involved in Na+ and Li+ effluxes in Saccharomyces cerevisiae has been isolated. The putative protein encoded by ENA2 differs only in thirteen amino acids from the protein encoded by ENA1/PMR2. However, ENA2 has a very low level of expression and for this reason did not confer significant Li+ tolerance on a Li+ sensitive strain. ENA1 and ENA2 are the first two units of a tandem array of four highly homologous genes with probably homologous functions.

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