Nuclear signaling by interleukin-6 - PubMed (original) (raw)
Review
Nuclear signaling by interleukin-6
S Chen-Kiang et al. Curr Opin Immunol. 1993 Feb.
Abstract
The molecular analysis of the regulation of nuclear proteins induced by interleukin-6 has provided new insights into this largely unknown signal transduction pathway. Transcription factors of the CCAAT/enhancer-binding protein and AP-1 families, as well as the octamer-binding proteins and the tumor suppressor gene product pRB, are regulated by interleukin-6 in a cell type specific manner, suggesting that they may play a role in the nuclear signaling by interleukin-6.
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