Autoimmune neutropenia - PubMed (original) (raw)
Review
. 1993 Apr 15;81(8):1984-95.
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- PMID: 8471760
Free article
Review
Autoimmune neutropenia
K A Shastri et al. Blood. 1993.
Free article
Abstract
There have been several new developments in the field of autoimmune neutropenia over the past decade. Neutropenia caused by antibodies directed against granulocyte precursor cells, the oligoclonal nature of antineutrophil antibodies, and the expanding knowledge of neutrophil antigens, particularly in relationship to autoantibodies, are exciting new areas of investigation. Knowledge has also been advanced in the effector mechanisms of neutrophil autoantibodies and the effect of autoantibodies on the neutrophil function. In addition, some clinical syndromes of immune neutropenia have been better defined over the past decade, such as autoimmune neutropenia of infancy and chronic idiopathic neutropenia in adults. The past decade also saw interesting developments in the treatment of immune neutropenia, particularly in the use of gammaglobulin preparations and more recently in the advent of hematopoietic growth factors. This review focuses on these newer aspects of autoimmune neutropenia.
Comment in
- Autoimmune neutropenia after bone marrow transplantation.
Klumpp TR, Herman JH. Klumpp TR, et al. Blood. 1993 Aug 1;82(3):1035. Blood. 1993. PMID: 8338935 No abstract available.
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