T-cell receptor beta-chain binding to enterotoxin superantigens - PubMed (original) (raw)
Review
T-cell receptor beta-chain binding to enterotoxin superantigens
M J Irwin et al. Immunol Rev. 1993 Feb.
Abstract
The last few years have seen an enormous jump in our knowledge and understanding of T-cell activation by superantigens. Clearly, a great number of infectious and parasitic organisms utilize superantigens as part of a strategy to evade the immune response of their host. The ability to modulate superantigen effects will give us new means to fight infections, and the knowledge of T-cell activation that we have gained from study of superantigens will, in turn, allow us to modulate the immune system in new ways.
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