Crystalline cylindrical structures of Na(+)-bound dimyristoylphosphatidylglycerol as revealed by microcalorimetry and electron microscopy - PubMed (original) (raw)

. 1993 Jun 12;1168(2):243-8.

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Crystalline cylindrical structures of Na(+)-bound dimyristoylphosphatidylglycerol as revealed by microcalorimetry and electron microscopy

M Kodama et al. Biochim Biophys Acta. 1993.

Abstract

Multilamellar vesicles of dimyristoylphosphatidylglycerol (DMPG) in an aqueous medium of 1 M NaCl at pH 7.0 converted to defined cylindrical structures of crystalline phase, on annealing of 5 degrees C of a gel phase temperature. The new crystalline phase transformed into the liquid crystal phase at a transition point (44.2 degrees C) nearly the same as that of the protonated DMPG, but with a transition enthalpy (19.2 kcal/mol) larger than that of the Ca(2+)-bound DMPG of much higher transition temperature. Electron microscopic observations revealed that a set of outer membranes (8-10 lamellae) separated from the MLV grows into helical structures and, finally, into the crystalline cylindrical structures with an increase in annealing time.

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