Integration of cell cycle control with transcriptional regulation by the retinoblastoma protein - PubMed (original) (raw)
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Integration of cell cycle control with transcriptional regulation by the retinoblastoma protein
R E Hollingsworth Jr et al. Curr Opin Cell Biol. 1993 Apr.
Abstract
Rapid progress in several areas of molecular biology has led to the realization that the retinoblastoma protein may play a pivotal role in the coordination between cell cycle control and regulation of gene expression. This role is a subtle one, and is important in only certain mammalian cell types. Exploring the details of these connections, and why only some cells rely on them, is already beginning to shed light on the regulation of cell multiplication.
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