Sodium citrate ingestion and muscle performance in acute hypobaric hypoxia - PubMed (original) (raw)

Clinical Trial

doi: 10.1007/BF00240418.

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Clinical Trial

Sodium citrate ingestion and muscle performance in acute hypobaric hypoxia

C Hausswirth et al. Eur J Appl Physiol Occup Physiol. 1995.

Abstract

Eight subjects were studied on four occasions following ingestion of a 300-ml solution containing either sodium citrate (C, 0.4 g.kg-1 body mass) or placebo (P, sodium chloride 0.045 g.kg-1 body mass), at local barometric pressure (N, PB approximately 740 mmHg, 98.7 kPa) or hypobaric hypoxia (HH, PB = 463 mmHg, 61.7 kPa). At 2 h after ingestion of the solution, the subjects performed prolonged isometric knee-extension at 35% of the maximal voluntary contraction (MVC) measured either in N or HH. Results showed that ingestion of C led to an improvement in muscle endurance (P < 0.01). However, this increase in endurance time for knee extensor muscles was only significant in N (+22%, P < 0.05, compared to +15%, NS, at N and HH, respectively). Following ingestion of sodium citrate, pre-exercise bicarbonate concentrations and pH levels were significantly higher than those measured after P ingestion. A significant treatment effect was observed for blood lactate concentrations with values higher for C than for P after 4, 6 and 10 min of recovery (P < 0.05). Electromyographic signals (EMG) were obtained from the vastus lateralis muscle during the prolonged isometric contraction at 35% MVC. The mean power frequency (MPF) significantly decreased in time under both N-P and N-C conditions. In HH, no significant decrease in MPF was observed with time. The results suggest that C ingestion was an ergogenic aid enhancing endurance during a sustained isometric contraction. In addition, it is suggested that fatigue during prolonged isometric contraction in HH was not directly related to factors determining the EMG signs of fatigue.

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References

    1. Eur J Appl Physiol Occup Physiol. 1988;58(1-2):20-5 - PubMed
    1. Eur J Appl Physiol Occup Physiol. 1977 Oct 31;37(3):197-204 - PubMed
    1. Eur J Appl Physiol Occup Physiol. 1986;55(5):524-9 - PubMed
    1. Eur J Appl Physiol Occup Physiol. 1992;64(1):36-41 - PubMed
    1. Can J Physiol Pharmacol. 1980 Jun;58(6):624-32 - PubMed

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