Prevention of disease progression, left ventricular hypertrophy and congestive heart failure in hypertension treatment trials - PubMed (original) (raw)
Meta-Analysis
Prevention of disease progression, left ventricular hypertrophy and congestive heart failure in hypertension treatment trials
M Moser et al. J Am Coll Cardiol. 1996 Apr.
Free article
Abstract
Objectives: This work was done to determine the role of hypertension treatment in the prevention of disease progression, left ventricular hypertrophy and congestive heart failure.
Background: Lowering of blood pressure in hypertensive patients has been reported to reduce morbidity and mortality from strokes and myocardial infarction. Data on primary prevention of disease progression, left ventricular hypertrophy and congestive heart failure have not previously been carefully quantified.
Methods: All the major long-term hypertension treatment trials over the past 20 years were reviewed.
Results: One thousand four hundred ninety-three of 13,342 subjects in the control groups compared with only 95 of 13,389 in the treated groups progressed from less severe to severe hypertension. The incidence of left ventricular hypertrophy in treated compared with control or placebo subjects was 140 of 6,150 and 216 of 6,098 subjects, respectively; congestive heart failure occurred in 240 of 6,923 subjects in the control group compared with only 112 of 6,914 treated subjects.
Conclusions: The lowering of blood pressure over a 3- to 5-year period of time is effective in preventing severe disease, left ventricular hypertrophy and congestive heart failure in addition to strokes and myocardial infarction. In an era when expensive and often complicated methods are being used to prevent recurrence of congestive heart failure or myocardial infarction, it is important to highlight the role of antihypertensive therapy in primary prevention.
Similar articles
- From left ventricular hypertrophy to congestive heart failure: management of hypertensive heart disease.
Gradman AH, Alfayoumi F. Gradman AH, et al. Prog Cardiovasc Dis. 2006 Mar-Apr;48(5):326-41. doi: 10.1016/j.pcad.2006.02.001. Prog Cardiovasc Dis. 2006. PMID: 16627048 Review. - [The primary and secondary prevention of hypertensive cardiopathy].
Agabiti-Rosei E, Muiesan ML. Agabiti-Rosei E, et al. Ital Heart J. 2000 Jun;1 Suppl 2:59-66. Ital Heart J. 2000. PMID: 10905130 Review. Italian. - Empiric determination of the transition from concentric hypertrophy to congestive heart failure in essential hypertension.
Shimizu G, Hirota Y, Kawamura K. Shimizu G, et al. J Am Coll Cardiol. 1995 Mar 15;25(4):888-94. doi: 10.1016/0735-1097(94)00474-5. J Am Coll Cardiol. 1995. PMID: 7884093 - Is left ventricular systolic dysfunction in hypertensive patients with heart failure normalized by long-term antihypertensive therapy?
Hamada M, Ohtani T, Suzuki M, Lin M, Kobayashi T, Okayama H, Takezaki M, Hashida K, Abe M, Matsuoka H, et al. Hamada M, et al. J Cardiol. 1993;23(2):165-75. J Cardiol. 1993. PMID: 8176628 - Left ventricular hypertrophy and heart failure in women.
Agabiti-Rosei E, Muiesan ML. Agabiti-Rosei E, et al. J Hypertens Suppl. 2002 May;20(2):S34-8. J Hypertens Suppl. 2002. PMID: 12183849 Review.
Cited by
- The Concept of "Heart Failure with Preserved Ejection Fraction": Time for a Critical Reappraisal.
Fragasso G. Fragasso G. Rev Cardiovasc Med. 2023 Jul 14;24(7):202. doi: 10.31083/j.rcm2407202. eCollection 2023 Jul. Rev Cardiovasc Med. 2023. PMID: 39076999 Free PMC article. Review. - A systematic review about the importance of neuropsychological features in heart failure: is at heart the only failure?
Chiatto LM, Corallo F, Calabrò RS, Cardile D, Pagano M, Cappadona I. Chiatto LM, et al. Neurol Sci. 2024 Aug;45(8):3611-3624. doi: 10.1007/s10072-024-07534-4. Epub 2024 Apr 17. Neurol Sci. 2024. PMID: 38632177 Review. - Hypertensive Heart Failure.
Triposkiadis F, Sarafidis P, Briasoulis A, Magouliotis DE, Athanasiou T, Skoularigis J, Xanthopoulos A. Triposkiadis F, et al. J Clin Med. 2023 Aug 2;12(15):5090. doi: 10.3390/jcm12155090. J Clin Med. 2023. PMID: 37568493 Free PMC article. Review. - Long-Term Exposure to Air Pollution, Road Traffic Noise, and Heart Failure Incidence: The Danish Nurse Cohort.
Lim YH, Jørgensen JT, So R, Cole-Hunter T, Mehta AJ, Amini H, Bräuner EV, Westendorp RGJ, Liu S, Mortensen LH, Hoffmann B, Loft S, Ketzel M, Hertel O, Brandt J, Jensen SS, Backalarz C, Simonsen MK, Tasic N, Maric M, Andersen ZJ. Lim YH, et al. J Am Heart Assoc. 2021 Oct 19;10(20):e021436. doi: 10.1161/JAHA.121.021436. Epub 2021 Oct 6. J Am Heart Assoc. 2021. PMID: 34612059 Free PMC article. - Risk factors and prediction models for incident heart failure with reduced and preserved ejection fraction.
Gaziano L, Cho K, Djousse L, Schubert P, Galloway A, Ho YL, Kurgansky K, Gagnon DR, Russo JP, Di Angelantonio E, Wood AM, Danesh J, Gaziano JM, Butterworth AS, Wilson PWF, Joseph J. Gaziano L, et al. ESC Heart Fail. 2021 Dec;8(6):4893-4903. doi: 10.1002/ehf2.13429. Epub 2021 Sep 16. ESC Heart Fail. 2021. PMID: 34528757 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Miscellaneous