Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain - PubMed (original) (raw)

• Clinically relevant dimer interface mutants of STAT1 transcription factor exhibit differential gene expression.
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• Protein Tyrosine Phosphatases: Regulators of CD4 T Cells in Inflammatory Bowel Disease.
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• Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset.
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• T helper type 2 cell differentiation occurs in the presence of interleukin 12 receptor beta2 chain expression and signaling.
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• Selective STAT protein degradation induced by paramyxoviruses requires both STAT1 and STAT2 but is independent of alpha/beta interferon signal transduction.
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