Community respiratory virus infections among hospitalized adult bone marrow transplant recipients - PubMed (original) (raw)
doi: 10.1093/clinids/22.5.778.
R E Champlin, R B Couch, J A Englund, J M Goodrich, I Raad, D Przepiorka, V A Lewis, N Mirza, H Yousuf, J J Tarrand, G P Bodey
Affiliations
- PMID: 8722930
- DOI: 10.1093/clinids/22.5.778
Community respiratory virus infections among hospitalized adult bone marrow transplant recipients
E Whimbey et al. Clin Infect Dis. 1996 May.
Abstract
From 1 November 1992 through 1 May 1993 and from 1 November 1993 through 1 May 1994, we conducted a prospective surveillance study at the University of Texas M.D. Anderson Cancer Center (Houston) to evaluate the role of community respiratory virus infections in hospitalized adult bone marrow transplant (BMT) recipients, Respiratory secretions were obtained from all adult BMT recipients with acute respiratory illnesses. During these two winters, a community respiratory virus was isolated from 37 (36%) of 102 patients and 30 (26%) of 115 patients, respectively. Approximately half (49%) of these infections were due to respiratory syncytial virus (RSV); the remainder were due to influenza virus (18%), picornaviruses (18%), parainfluenza virus (9%), or adenovirus (6%). Fifty-eight percent of these infections were complicated by pneumonia, with an associated mortality of 51%. The pneumonias that complicated RSV infection were almost exclusively viral in origin and were associated with a mortality of 100% if not treated promptly with antiviral agents. In contrast, many of the pneumonias that complicated the other viral infections, such as influenza, appeared to be either self-limited viral pneumonias or secondary bacterial or fungal pneumonias. Community respiratory viruses are frequent causes of acute respiratory illnesses in adult BMT recipients hospitalized during the winter and are associated with substantial morbidity and mortality.
Similar articles
- Respiratory virus infections in bone marrow transplant recipients: the European perspective.
Ljungman P. Ljungman P. Am J Med. 1997 Mar 17;102(3A):44-7. doi: 10.1016/s0002-9343(97)00010-7. Am J Med. 1997. PMID: 10868142 - Community respiratory virus infections in immunocompromised patients with cancer.
Whimbey E, Englund JA, Couch RB. Whimbey E, et al. Am J Med. 1997 Mar 17;102(3A):10-8; discussion 25-6. doi: 10.1016/s0002-9343(97)80004-6. Am J Med. 1997. PMID: 10868137 Free PMC article. Review. - The incidence of respiratory tract infection in adults requiring hospitalization for asthma.
Teichtahl H, Buckmaster N, Pertnikovs E. Teichtahl H, et al. Chest. 1997 Sep;112(3):591-6. doi: 10.1378/chest.112.3.591. Chest. 1997. PMID: 9315789 Free PMC article. - Respiratory virus infections after marrow transplant: the Fred Hutchinson Cancer Research Center experience.
Bowden RA. Bowden RA. Am J Med. 1997 Mar 17;102(3A):27-30; discussion 42-3. doi: 10.1016/s0002-9343(97)00007-7. Am J Med. 1997. PMID: 10868139 Clinical Trial. - Management of respiratory viral infections in hematopoietic cell transplant recipients and patients with hematologic malignancies.
Chemaly RF, Shah DP, Boeckh MJ. Chemaly RF, et al. Clin Infect Dis. 2014 Nov 15;59 Suppl 5(Suppl 5):S344-51. doi: 10.1093/cid/ciu623. Clin Infect Dis. 2014. PMID: 25352629 Free PMC article. Review.
Cited by
- Identification of Lower Respiratory Tract Pathogens in Cancer Patients: Insights into Fatal Outcomes.
Mourad DF, Radwan S, Hamdy R, Elkhashab DM, Kamel MM, Abdel-Moneim AS, Kadry DY. Mourad DF, et al. Microorganisms. 2024 Aug 16;12(8):1686. doi: 10.3390/microorganisms12081686. Microorganisms. 2024. PMID: 39203528 Free PMC article. - Respiratory Syncytial Virus Infections in Recipients of Bone Marrow Transplants: A Systematic Review and Meta-Analysis.
Riccò M, Parisi S, Corrado S, Marchesi F, Bottazzoli M, Gori D. Riccò M, et al. Infect Dis Rep. 2024 Mar 29;16(2):317-355. doi: 10.3390/idr16020026. Infect Dis Rep. 2024. PMID: 38667752 Free PMC article. Review. - Comparative Analysis of Clinical Outcomes for COVID-19 and Influenza among Cardiac Transplant Recipients in the United States.
Chavarin DJ, Bobba A, Davis MG, Roth MA, Kasdorf M, Nasrullah A, Chourasia P, Gangu K, Avula SR, Sheikh AB. Chavarin DJ, et al. Viruses. 2023 Aug 5;15(8):1700. doi: 10.3390/v15081700. Viruses. 2023. PMID: 37632042 Free PMC article. - Respiratory Syncytial Virus Infection among Adults after Hematopoietic Stem Cell Transplantation.
Samad SA, Jethani J, Kumar L, Choudhary A, Brijwal M, Dar L. Samad SA, et al. J Glob Infect Dis. 2022 Aug 26;14(3):112-116. doi: 10.4103/jgid.jgid_11_22. eCollection 2022 Jul-Sep. J Glob Infect Dis. 2022. PMID: 36237564 Free PMC article. - DAS181 Treatment of Severe Lower Respiratory Tract Parainfluenza Virus Infection in Immunocompromised Patients: A Phase 2 Randomized, Placebo-Controlled Study.
Chemaly RF, Marty FM, Wolfe CR, Lawrence SJ, Dadwal S, Soave R, Farthing J, Hawley S, Montanez P, Hwang J, Ho JH, Lewis S, Wang G, Boeckh M. Chemaly RF, et al. Clin Infect Dis. 2021 Aug 2;73(3):e773-e781. doi: 10.1093/cid/ciab113. Clin Infect Dis. 2021. PMID: 33569576 Free PMC article. Clinical Trial.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical