Transcriptional repression in development - PubMed (original) (raw)
Review
Transcriptional repression in development
S Gray et al. Curr Opin Cell Biol. 1996 Jun.
Abstract
It is becoming increasingly clear that transcriptional repression is at least as important as transcriptional activation for establishing cell-type specific patterns of gene expression during embryogenesis. Recent studies in Drosophila suggest that repressors fall into two categories, short-range and long-range repressors. The former permit enhancer autonomy in modular promoters, whereas the latter function in a dominant fashion to silence multiple enhancers.
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