Evolution of the intron-exon structure of eukaryotic genes - PubMed (original) (raw)
Review
Evolution of the intron-exon structure of eukaryotic genes
M Long et al. Curr Opin Genet Dev. 1995 Dec.
Abstract
The origin and evolution of intron-exon structures continue to be controversial topics. Two alternative theories, the 'exon theory of genes' and the 'insertional theory of introns', debate the presence or absence of introns in primordial genes. Both sides of the argument have focused on the positions of introns with respect to protein and gene structures. A new approach has emerged in the study of the evolution of intron-exon structures: a population analysis of genes. One example is the statistical analysis of intron phases--the position of introns within or between codons. This analysis detected a significant signal of exon shuffling in the DNA sequence database containing both ancient and modern exon sequences: intron phase correlations, that is, the association together within genes of introns of the same phase. The results of this analysis suggest that exon shuffling played an important role in the origin of both ancient and modern genes.
Similar articles
- Intron phase correlations and the evolution of the intron/exon structure of genes.
Long M, Rosenberg C, Gilbert W. Long M, et al. Proc Natl Acad Sci U S A. 1995 Dec 19;92(26):12495-9. doi: 10.1073/pnas.92.26.12495. Proc Natl Acad Sci U S A. 1995. PMID: 8618928 Free PMC article. - Toward a resolution of the introns early/late debate: only phase zero introns are correlated with the structure of ancient proteins.
de Souza SJ, Long M, Klein RJ, Roy S, Lin S, Gilbert W. de Souza SJ, et al. Proc Natl Acad Sci U S A. 1998 Apr 28;95(9):5094-9. doi: 10.1073/pnas.95.9.5094. Proc Natl Acad Sci U S A. 1998. PMID: 9560234 Free PMC article. - Analysis of evolution of exon-intron structure of eukaryotic genes.
Rogozin IB, Sverdlov AV, Babenko VN, Koonin EV. Rogozin IB, et al. Brief Bioinform. 2005 Jun;6(2):118-34. doi: 10.1093/bib/6.2.118. Brief Bioinform. 2005. PMID: 15975222 Review. - Can codon usage bias explain intron phase distributions and exon symmetry?
Ruvinsky A, Eskesen ST, Eskesen FN, Hurst LD. Ruvinsky A, et al. J Mol Evol. 2005 Jan;60(1):99-104. doi: 10.1007/s00239-004-0032-9. J Mol Evol. 2005. PMID: 15696372 - Recent evidence for the exon theory of genes.
Roy SW. Roy SW. Genetica. 2003 Jul;118(2-3):251-66. Genetica. 2003. PMID: 12868614 Review.
Cited by
- Identification of New Cultivar and Different Provenances of Dendrocalamus brandisii (Poaceae: Bambusoideae) Using Simple Sequence Repeats Developed from the Whole Genome.
Geng R, Xu J, Jiang J, Cheng Z, Sun M, Xia N, Gao J. Geng R, et al. Plants (Basel). 2024 Oct 17;13(20):2910. doi: 10.3390/plants13202910. Plants (Basel). 2024. PMID: 39458856 Free PMC article. - Jasmonate ZIM Domain Protein (JAZ) Gene SLJAZ15 Increases Resistance to Orobanche aegyptiaca in Tomato.
Chen S, Zhang L, Ma Q, Chen M, Cao X, Zhao S, Zhang X. Chen S, et al. Plants (Basel). 2024 May 29;13(11):1493. doi: 10.3390/plants13111493. Plants (Basel). 2024. PMID: 38891302 Free PMC article. - Genome-wide identification of the OMT gene family in Cucumis melo L. and expression analysis under abiotic and biotic stress.
Wang S, Wang C, Lv F, Chu P, Jin H. Wang S, et al. PeerJ. 2023 Dec 14;11:e16483. doi: 10.7717/peerj.16483. eCollection 2023. PeerJ. 2023. PMID: 38107581 Free PMC article. - Exon Elongation Added Intrinsically Disordered Regions to the Encoded Proteins and Facilitated the Emergence of the Last Eukaryotic Common Ancestor.
Fukuchi S, Noguchi T, Anbo H, Homma K. Fukuchi S, et al. Mol Biol Evol. 2023 Jan 4;40(1):msac272. doi: 10.1093/molbev/msac272. Mol Biol Evol. 2023. PMID: 36529689 Free PMC article. - Genome-Wide Identification, Characterization and Expression Analysis of the JAZ Gene Family in Resistance to Gray Leaf Spots in Tomato.
Sun Y, Liu C, Liu Z, Zhao T, Jiang J, Li J, Xu X, Yang H. Sun Y, et al. Int J Mol Sci. 2021 Sep 15;22(18):9974. doi: 10.3390/ijms22189974. Int J Mol Sci. 2021. PMID: 34576142 Free PMC article.