Effect of surgical treatment on hypertension in Cushing's syndrome - PubMed (original) (raw)
Clinical Trial
Effect of surgical treatment on hypertension in Cushing's syndrome
F Fallo et al. Am J Hypertens. 1996 Jan.
Abstract
The effect of a surgical cure of hypercortisolism on hypertension in 54 patients with Cushing's syndrome was assessed. The correlation between preoperative duration of hypertension and posttreatment blood pressure was significant (P < .01). Restoration of normal cortisol was associated with blood pressure normalization in 39 out of 54 cases. Duration of hypertension of patients with normalized blood pressure was significantly shorter than that of patients with persistent hypertension postoperatively (P < .0001). Duration of hypertension, ie, long-lasting exposure to increased cortisol, appears to be the determinant of persistent hypertension following successful surgery in Cushing's syndrome.
Similar articles
- Effect of hypercortisolism control on high blood pressure in Cushing's syndrome.
Gómez RM, Albiger NM, Díaz AG, Moncet D, Pitoia FA, Bruno OD. Gómez RM, et al. Medicina (B Aires). 2007;67(5):439-44. Medicina (B Aires). 2007. PMID: 18051226 - Blood pressure in children and adolescents with Cushing's syndrome before and after surgical care.
Magiakou MA, Mastorakos G, Zachman K, Chrousos GP. Magiakou MA, et al. J Clin Endocrinol Metab. 1997 Jun;82(6):1734-8. doi: 10.1210/jcem.82.6.3985. J Clin Endocrinol Metab. 1997. PMID: 9177372 - Disproportionate hypertrophy of the interventricular septum and its regression in Cushing's syndrome. Report of three cases.
Sugihara N, Shimizu M, Shimizu K, Ino H, Miyamori I, Nakabayashi H, Takeda R. Sugihara N, et al. Intern Med. 1992 Mar;31(3):407-13. doi: 10.2169/internalmedicine.31.407. Intern Med. 1992. PMID: 1535248 - Hypertension in Cushing's syndrome.
Magiakou MA, Smyrnaki P, Chrousos GP. Magiakou MA, et al. Best Pract Res Clin Endocrinol Metab. 2006 Sep;20(3):467-82. doi: 10.1016/j.beem.2006.07.006. Best Pract Res Clin Endocrinol Metab. 2006. PMID: 16980206 Review. - Cushing's syndrome and hypertension.
Danese RD, Aron DC. Danese RD, et al. Endocrinol Metab Clin North Am. 1994 Jun;23(2):299-324. Endocrinol Metab Clin North Am. 1994. PMID: 8070424 Review.
Cited by
- Comorbidities in Cushing's disease.
Sharma ST, Nieman LK, Feelders RA. Sharma ST, et al. Pituitary. 2015 Apr;18(2):188-94. doi: 10.1007/s11102-015-0645-6. Pituitary. 2015. PMID: 25724314 Free PMC article. Review. - Glucocorticoid excess and hypertension.
Baid S, Nieman LK. Baid S, et al. Curr Hypertens Rep. 2004 Dec;6(6):493-9. doi: 10.1007/s11906-004-0046-0. Curr Hypertens Rep. 2004. PMID: 15527696 Review. - Psychiatric disorders associated with Cushing's syndrome. Epidemiology, pathophysiology and treatment.
Sonino N, Fava GA. Sonino N, et al. CNS Drugs. 2001;15(5):361-73. doi: 10.2165/00023210-200115050-00003. CNS Drugs. 2001. PMID: 11475942 Review. - Treatment of Cushing's Syndrome: An Endocrine Society Clinical Practice Guideline.
Nieman LK, Biller BM, Findling JW, Murad MH, Newell-Price J, Savage MO, Tabarin A; Endocrine Society. Nieman LK, et al. J Clin Endocrinol Metab. 2015 Aug;100(8):2807-31. doi: 10.1210/jc.2015-1818. Epub 2015 Jul 29. J Clin Endocrinol Metab. 2015. PMID: 26222757 Free PMC article. - Treatment of Cushing disease: overview and recent findings.
Mancini T, Porcelli T, Giustina A. Mancini T, et al. Ther Clin Risk Manag. 2010 Oct 21;6:505-16. doi: 10.2147/TCRM.S12952. Ther Clin Risk Manag. 2010. PMID: 21063461 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical