TAFs mediate transcriptional activation and promoter selectivity - PubMed (original) (raw)

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• PMID: 8870497

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TAFs mediate transcriptional activation and promoter selectivity

C P Verrijzer et al. Trends Biochem Sci. 1996 Sep.

Abstract

The TATA-binding protein (TBP)-associated factors (TAFs) of TFIID play a central role in RNA polymerase II transcriptional regulation. Some TAFs can function as co-activators that mediate the activation signal from enhancer-bound regulators. In addition, interactions between selected TAFs and core elements direct promoter selectivity by RNA polymerase II.

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• RNA polymerase II transcription control.
  Kornberg RD. Kornberg RD. Trends Biochem Sci. 1996 Sep;21(9):325-6. Trends Biochem Sci. 1996. PMID: 8870494 No abstract available.

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