TAFs mediate transcriptional activation and promoter selectivity - PubMed (original) (raw)
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- PMID: 8870497
Review
TAFs mediate transcriptional activation and promoter selectivity
C P Verrijzer et al. Trends Biochem Sci. 1996 Sep.
Abstract
The TATA-binding protein (TBP)-associated factors (TAFs) of TFIID play a central role in RNA polymerase II transcriptional regulation. Some TAFs can function as co-activators that mediate the activation signal from enhancer-bound regulators. In addition, interactions between selected TAFs and core elements direct promoter selectivity by RNA polymerase II.
Comment in
- RNA polymerase II transcription control.
Kornberg RD. Kornberg RD. Trends Biochem Sci. 1996 Sep;21(9):325-6. Trends Biochem Sci. 1996. PMID: 8870494 No abstract available.
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