Lymphocytes which differentiate in an allogeneic thymus. II. Evidence for both central and peripheral mechanisms in tolerance to donor strain tissues - PubMed (original) (raw)
Lymphocytes which differentiate in an allogeneic thymus. II. Evidence for both central and peripheral mechanisms in tolerance to donor strain tissues
B Kindred et al. Eur J Immunol. 1977 Jul.
Abstract
Nude mice which have been grafted with an allogeneic H-2-incompatible thymus are frequently specifically tolerant to skin grafts from the thymus donor strain. The evidence presented here indicates that both clonal deletion and peripheral suppressor cells play a part in maintaining this tolerance.
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