ADAMs and cell fusion - PubMed (original) (raw)

Review

ADAMs and cell fusion

A P Huovila et al. Curr Opin Cell Biol. 1996 Oct.

Abstract

Members of the ADAM family (membrane proteins with a disintegrin and metalloprotease domain) have been implicated in several cell-interactive events, including cell-cell fusion. Recent evidence implicates three ADAMs, fertilin-alpha, fertilin-beta, and meltrin-alpha, in sperm-egg fusion and myoblast fusion. In light of the large number and wide tissue distribution of the ADAMs, they may also participate in other cell-cell fusion events. As ADAMs are also found in both vertebrates and invertebrates, some features of cell-cell fusion reactions may be conserved throughout the animal kingdom.

PubMed Disclaimer

Similar articles

• A role for the disintegrin domain of cyritestin, a sperm surface protein belonging to the ADAM family, in mouse sperm-egg plasma membrane adhesion and fusion.
  Yuan R, Primakoff P, Myles DG. Yuan R, et al. J Cell Biol. 1997 Apr 7;137(1):105-12. doi: 10.1083/jcb.137.1.105. J Cell Biol. 1997. PMID: 9105040 Free PMC article.
• Fertilin beta and other ADAMs as integrin ligands: insights into cell adhesion and fertilization.
  Evans JP. Evans JP. Bioessays. 2001 Jul;23(7):628-39. doi: 10.1002/bies.1088. Bioessays. 2001. PMID: 11462216 Review.
• Identification of key functional amino acids of the mouse fertilin beta (ADAM2) disintegrin loop for cell-cell adhesion during fertilization.
  Zhu X, Bansal NP, Evans JP. Zhu X, et al. J Biol Chem. 2000 Mar 17;275(11):7677-83. doi: 10.1074/jbc.275.11.7677. J Biol Chem. 2000. PMID: 10713078

Cited by

• Phenotype Compensation in Reproductive ADAM Gene Family: A Case Study with ADAM27 Knockout Mouse.
  Khezri J, Hasheni E, Shams Ara M, Rahim Tayefe A, Heidari F. Khezri J, et al. Iran J Biotechnol. 2022 Oct 1;20(4):e2902. doi: 10.30498/ijb.2022.250175.2902. eCollection 2022 Oct. Iran J Biotechnol. 2022. PMID: 38344314 Free PMC article.
• Human cyritestin genes (CYRN1 and CYRN2) are non-functional.
  Grzmil P, Kim Y, Shamsadin R, Neesen J, Adham IM, Heinlein UA, Schwarzer UJ, Engel W. Grzmil P, et al. Biochem J. 2001 Jul 15;357(Pt 2):551-6. doi: 10.1042/0264-6021:3570551. Biochem J. 2001. PMID: 11439107 Free PMC article.
• Establishment of an in vitro assay to measure the invasion of ovarian carcinoma cells through mesothelial cell monolayers.
  Casey RC, Koch KA, Oegema TR Jr, Skubitz KM, Pambuccian SE, Grindle SM, Skubitz AP. Casey RC, et al. Clin Exp Metastasis. 2003;20(4):343-56. doi: 10.1023/a:1024009131191. Clin Exp Metastasis. 2003. PMID: 12856722
• ADAM 33 and its association with airway remodeling and hyperresponsiveness in asthma.
  Holgate ST, Davies DE, Rorke S, Cakebread J, Murphy G, Powell RM, Holloway JW. Holgate ST, et al. Clin Rev Allergy Immunol. 2004 Aug;27(1):23-34. doi: 10.1385/CRIAI:27:1:023. Clin Rev Allergy Immunol. 2004. PMID: 15347848 Review.
• Mitochondrial fusion in yeast requires the transmembrane GTPase Fzo1p.
  Hermann GJ, Thatcher JW, Mills JP, Hales KG, Fuller MT, Nunnari J, Shaw JM. Hermann GJ, et al. J Cell Biol. 1998 Oct 19;143(2):359-73. doi: 10.1083/jcb.143.2.359. J Cell Biol. 1998. PMID: 9786948 Free PMC article.

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Elsevier Science

• Other Literature Sources

  • The Lens - Patent Citations Database

• Research Materials

  • NCI CPTC Antibody Characterization Program