Structure of nucleosome core particles of chromatin - PubMed (original) (raw)
. 1977 Sep 1;269(5623):29-36.
doi: 10.1038/269029a0.
- PMID: 895884
- DOI: 10.1038/269029a0
Structure of nucleosome core particles of chromatin
J T Finch et al. Nature. 1977.
Abstract
Cystals have been obtained on nucleosome cores and analysed by X-ray diffraction and electron microscopy. The core is a flat particle of dimensions about 110 X 110 X 57 A, somewhat wedge shaped, and strongly divided into two 'layers', consistent with the DNA being wound into about 1 3/4 turns of a flat superhelix of a pitch about 28 A. The organisation of the DNA can be correlated with the results to enzyme digestion studies. A change in the screw of the DNA double helix on nucleosome formation can be deduced.
Similar articles
- X-ray and electron microscope analyses of crystals of nucleosome cores.
Finch JT, Klug A. Finch JT, et al. Cold Spring Harb Symp Quant Biol. 1978;42 Pt 1:1-9. doi: 10.1101/sqb.1978.042.01.003. Cold Spring Harb Symp Quant Biol. 1978. PMID: 277331 No abstract available. - Conformation of nucleosome core particles and chromatin in high salt concentration.
Wilhelm ML, Wilhelm FX. Wilhelm ML, et al. Biochemistry. 1980 Sep 2;19(18):4327-31. doi: 10.1021/bi00559a028. Biochemistry. 1980. PMID: 7417408 - X-ray structure of the nucleosome core particle.
Uberbacher EC, Bunick GJ. Uberbacher EC, et al. J Biomol Struct Dyn. 1985 Jun;2(6):1033-55. doi: 10.1080/07391102.1985.10507623. J Biomol Struct Dyn. 1985. PMID: 3916941 - Chromatin.
Felsenfeld G. Felsenfeld G. Nature. 1978 Jan 12;271(5641):115-22. doi: 10.1038/271115a0. Nature. 1978. PMID: 340956 Review. - Structure and function of chromatin.
Lilley DM, Pardon JF. Lilley DM, et al. Annu Rev Genet. 1979;13:197-233. doi: 10.1146/annurev.ge.13.120179.001213. Annu Rev Genet. 1979. PMID: 231929 Review. No abstract available.
Cited by
- The nucleosome reference frame and standard geometries for octasomes.
Sun R, Bishop T. Sun R, et al. Biophys Rev. 2024 Jul 19;16(3):315-330. doi: 10.1007/s12551-024-01206-5. eCollection 2024 Jun. Biophys Rev. 2024. PMID: 39099844 Review. - Bacterial chromatin proteins, transcription, and DNA topology: Inseparable partners in the control of gene expression.
Hustmyer CM, Landick R. Hustmyer CM, et al. Mol Microbiol. 2024 Jul;122(1):81-112. doi: 10.1111/mmi.15283. Epub 2024 Jun 7. Mol Microbiol. 2024. PMID: 38847475 Review. - The Free Energy of Nucleosomal DNA Based on the Landau Model and Topology.
Yang H, Shi X. Yang H, et al. Biomolecules. 2023 Nov 23;13(12):1686. doi: 10.3390/biom13121686. Biomolecules. 2023. PMID: 38136559 Free PMC article. - The Effects of Histone H2B Ubiquitylations on the Nucleosome Structure and Internucleosomal Interactions.
Sengupta B, Huynh M, Smith CB, McGinty RK, Krajewski W, Lee TH. Sengupta B, et al. Biochemistry. 2022 Oct 18;61(20):2198-2205. doi: 10.1021/acs.biochem.2c00422. Epub 2022 Sep 16. Biochemistry. 2022. PMID: 36112542 Free PMC article. - Nucleosome Structures Built from Highly Divergent Histones: Parasites and Giant DNA Viruses.
Sato S, Dacher M, Kurumizaka H. Sato S, et al. Epigenomes. 2022 Aug 2;6(3):22. doi: 10.3390/epigenomes6030022. Epigenomes. 2022. PMID: 35997368 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources