Transport of proteins in eukaryotic cells: more questions ahead - PubMed (original) (raw)
Review
. 1996 Oct;32(1-2):223-49.
doi: 10.1007/BF00039384.
Affiliations
- PMID: 8980481
- DOI: 10.1007/BF00039384
Review
Transport of proteins in eukaryotic cells: more questions ahead
M Bar-Peled et al. Plant Mol Biol. 1996 Oct.
Abstract
Some newly synthesized proteins contain signals that direct their transport to their final location within or outside of the cell. Targeting signals are recognized by specific protein receptors located either in the cytoplasm or in the membrane of the target organelle. Specific membrane protein complexes are involved in insertion and translocation of polypeptides across the membranes. Often, additional targeting signals are required for a polypeptide to be further transported to its site of function. In this review, we will describe the trafficking of proteins to various cellular organelles (nucleus, chloroplasts, mitochondria, peroxisomes) with emphasis on transport to and through the secretory pathway.
Similar articles
- The Design and Structure of Outer Membrane Receptors from Peroxisomes, Mitochondria, and Chloroplasts.
Panigrahi R, Kubiszewski-Jakubiak S, Whelan J, Vrielink A. Panigrahi R, et al. Structure. 2015 Oct 6;23(10):1783-1800. doi: 10.1016/j.str.2015.08.005. Epub 2015 Sep 10. Structure. 2015. PMID: 26365798 Review. - Protein transport via amino-terminal targeting sequences: common themes in diverse systems.
Rusch SL, Kendall DA. Rusch SL, et al. Mol Membr Biol. 1995 Oct-Dec;12(4):295-307. doi: 10.3109/09687689509072431. Mol Membr Biol. 1995. PMID: 8747274 Review. - Protein translocation machineries: how organelles bring in matrix proteins.
Gunkel K, Veenhuis M, van der Klei IJ. Gunkel K, et al. FEMS Yeast Res. 2005 Nov;5(11):1037-45. doi: 10.1016/j.femsyr.2005.03.004. FEMS Yeast Res. 2005. PMID: 16269392 Review. - Protein trafficking in plant cells: Tools and markers.
Zhu D, Zhang M, Gao C, Shen J. Zhu D, et al. Sci China Life Sci. 2020 Mar;63(3):343-363. doi: 10.1007/s11427-019-9598-3. Epub 2019 Nov 7. Sci China Life Sci. 2020. PMID: 31707539 Review. - Protein translocation across membranes.
Agarraberes FA, Dice JF. Agarraberes FA, et al. Biochim Biophys Acta. 2001 Jul 2;1513(1):1-24. doi: 10.1016/s0304-4157(01)00005-3. Biochim Biophys Acta. 2001. PMID: 11427190 Review.
Cited by
- Secretion trap tagging of secreted and membrane-spanning proteins using Arabidopsis gene traps.
Groover AT, Fontana JR, Arroyo JM, Yordan C, McCombie WR, Martienssen RA. Groover AT, et al. Plant Physiol. 2003 Jun;132(2):698-708. doi: 10.1104/pp.103.020099. Epub 2003 Apr 24. Plant Physiol. 2003. PMID: 12805598 Free PMC article. - Zein protein interactions, rather than the asymmetric distribution of zein mRNAs on endoplasmic reticulum membranes, influence protein body formation in maize endosperm.
Kim CS, Woo Ym YM, Clore AM, Burnett RJ, Carneiro NP, Larkins BA. Kim CS, et al. Plant Cell. 2002 Mar;14(3):655-72. doi: 10.1105/tpc.010431. Plant Cell. 2002. PMID: 11910012 Free PMC article. - Tomato spotted wilt virus glycoproteins exhibit trafficking and localization signals that are functional in mammalian cells.
Kikkert M, Verschoor A, Kormelink R, Rottier P, Goldbach R. Kikkert M, et al. J Virol. 2001 Jan;75(2):1004-12. doi: 10.1128/JVI.75.2.1004-1012.2001. J Virol. 2001. PMID: 11134314 Free PMC article. - Identification of BFN1, a bifunctional nuclease induced during leaf and stem senescence in Arabidopsis.
Pérez-Amador MA, Abler ML, De Rocher EJ, Thompson DM, van Hoof A, LeBrasseur ND, Lers A, Green PJ. Pérez-Amador MA, et al. Plant Physiol. 2000 Jan;122(1):169-80. doi: 10.1104/pp.122.1.169. Plant Physiol. 2000. PMID: 10631260 Free PMC article.
References
- EMBO J. 1993 Nov;12 (11):4083-93 - PubMed
- J Biol Chem. 1994 Mar 25;269(12):9045-51 - PubMed
- EMBO J. 1995 Aug 15;14(16):3905-14 - PubMed
- Cell. 1990 Jun 15;61(6):1063-74 - PubMed
- EMBO J. 1993 Nov;12 (11):4125-35 - PubMed