Bafilomycins and concanamycins as inhibitors of V-ATPases and P-ATPases - PubMed (original) (raw)
Review
. 1997 Jan;200(Pt 1):1-8.
doi: 10.1242/jeb.200.1.1.
Affiliations
- PMID: 9023991
- DOI: 10.1242/jeb.200.1.1
Review
Bafilomycins and concanamycins as inhibitors of V-ATPases and P-ATPases
S Dröse et al. J Exp Biol. 1997 Jan.
Abstract
Bafilomycins and concanamycins, two groups of the plecomacrolide-defined class of macrolide antibiotics, have recently been recognized as important tools for studying the physiological role of vacuolar-type, proton-translocating ATPases (V-ATPases) and ATPases with phosphorylated states (P-ATPases) in animal and plant cells as well as in yeast, fungi and bacteria. The following review will give an account of the classification and function of these antibiotics.
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