Anchorage-dependent cell cycle progression - PubMed (original) (raw)

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Anchorage-dependent cell cycle progression

R K Assoian. J Cell Biol. 1997.

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Figure 1

Figure 1

Coordinated control of G1 phase cell cycle progression by growth factors and the extracellular matrix (ECM). A working model showing the major sites of growth factor and ECM action (solid arrows) during cell cycle progression from G0 to S phase. Cyclin E gene expression is strongly pRb/E2F dependent, but the cyclin E protein is stable and present in G1 phase cells both before and after pRb phosphorylation. Regulatory phosphorylations and the roles of INK4s are not shown.

References

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