Identification and characterization of genomic nucleosome-positioning sequences - PubMed (original) (raw)
. 1997 Apr 11;267(4):807-17.
doi: 10.1006/jmbi.1997.0916.
Affiliations
- PMID: 9135113
- DOI: 10.1006/jmbi.1997.0916
Free article
Identification and characterization of genomic nucleosome-positioning sequences
H R Widlund et al. J Mol Biol. 1997.
Free article
Abstract
Positioned nucleosomes are believed to play important roles in transcriptional regulation and for the organization of chromatin in cell nuclei. Here, we have isolated the DNA segments in the mouse genome that form the most stable nucleosomes yet characterized. In separate molecules we find phased runs of three to four adenine nucleotides, extensive CA repeats, and in a few cases phased TATA tetranucleotides. The latter forms the most stable nucleosome yet characterized. One sequence with CAG repeats was also found. By fluorescence in situ hydridization the selected sequences are shown to be localized at the centromeric regions of mouse metaphase chromosomes.
Similar articles
- New types of mouse centromeric satellite DNAs.
Kuznetsova IS, Prusov AN, Enukashvily NI, Podgornaya OI. Kuznetsova IS, et al. Chromosome Res. 2005;13(1):9-25. doi: 10.1007/s10577-005-2346-x. Chromosome Res. 2005. PMID: 15791408 - TGGA repeats impair nucleosome formation.
Cao H, Widlund HR, Simonsson T, Kubista M. Cao H, et al. J Mol Biol. 1998 Aug 14;281(2):253-60. doi: 10.1006/jmbi.1998.1925. J Mol Biol. 1998. PMID: 9698546 - Archaeal histone selection of nucleosome positioning sequences and the procaryotic origin of histone-dependent genome evolution.
Bailey KA, Pereira SL, Widom J, Reeve JN. Bailey KA, et al. J Mol Biol. 2000 Oct 13;303(1):25-34. doi: 10.1006/jmbi.2000.4128. J Mol Biol. 2000. PMID: 11021967 - Satellite DNAs between selfishness and functionality: structure, genomics and evolution of tandem repeats in centromeric (hetero)chromatin.
Plohl M, Luchetti A, Mestrović N, Mantovani B. Plohl M, et al. Gene. 2008 Feb 15;409(1-2):72-82. doi: 10.1016/j.gene.2007.11.013. Epub 2007 Dec 4. Gene. 2008. PMID: 18182173 Review. - Review fifteen years of search for strong nucleosomes.
Trifonov EN, Nibhani R. Trifonov EN, et al. Biopolymers. 2015 Aug;103(8):432-7. doi: 10.1002/bip.22604. Biopolymers. 2015. PMID: 25546738 Review.
Cited by
- A study of strong nucleosomes in the human genome.
Wang L, Dong C, Lu C, Li S, Fu L, Cong B. Wang L, et al. iScience. 2022 Jun 13;25(7):104593. doi: 10.1016/j.isci.2022.104593. eCollection 2022 Jul 15. iScience. 2022. PMID: 35789840 Free PMC article. - Coupling between Sequence-Mediated Nucleosome Organization and Genome Evolution.
Barbier J, Vaillant C, Volff JN, Brunet FG, Audit B. Barbier J, et al. Genes (Basel). 2021 Jun 1;12(6):851. doi: 10.3390/genes12060851. Genes (Basel). 2021. PMID: 34205881 Free PMC article. Review. - Atomistic insight into sequence-directed DNA bending and minicircle formation propensity in the absence and presence of phased A-tracts.
Mills A, Gago F. Mills A, et al. J Comput Aided Mol Des. 2020 Mar;34(3):253-265. doi: 10.1007/s10822-020-00288-z. Epub 2020 Jan 16. J Comput Aided Mol Des. 2020. PMID: 31950463 - Contributions of Sequence to the Higher-Order Structures of DNA.
Todolli S, Perez PJ, Clauvelin N, Olson WK. Todolli S, et al. Biophys J. 2017 Feb 7;112(3):416-426. doi: 10.1016/j.bpj.2016.11.017. Epub 2016 Dec 9. Biophys J. 2017. PMID: 27955889 Free PMC article. Review. - A novel hypothesis for histone-to-protamine transition in Bos taurus spermatozoa.
Sillaste G, Kaplinski L, Meier R, Jaakma Ü, Eriste E, Salumets A. Sillaste G, et al. Reproduction. 2017 Mar;153(3):241-251. doi: 10.1530/REP-16-0441. Epub 2016 Nov 29. Reproduction. 2017. PMID: 27899719 Free PMC article.