CD4-independent infection by HIV-2 (ROD/B): use of the 7-transmembrane receptors CXCR-4, CCR-3, and V28 for entry - PubMed (original) (raw)
. 1997 Apr 28;231(1):130-4.
doi: 10.1006/viro.1997.8508.
Affiliations
- PMID: 9143311
- DOI: 10.1006/viro.1997.8508
Free article
CD4-independent infection by HIV-2 (ROD/B): use of the 7-transmembrane receptors CXCR-4, CCR-3, and V28 for entry
J D Reeves et al. Virology. 1997.
Free article
Abstract
We have assayed a variety of 7tm chemokine receptors (CCR-2b, CCR-3, CCR-4, CCR-5, CXCR-1, CXCR-4) and two orphan 7tm receptors (V28 and EBI.1) for their ability to allow infection of CD4-negative feline kidney CCC cells by the HIV-2 strains ROD/A and ROD/B. We found that ROD/B was able to use CXCR-4 transiently expressed in CCC cells, and infection by ROD/A was enhanced 15-fold in the presence of sCD4. Feline CCC cells also became permissive to ROD/B and ROD/A entry when transiently transfected with the chemokine receptor CCR-3 or the orphan 7tm receptor V2B, when cultured in the presence of sCD4. Entry of ROD/A into CCC cells expressing CCR-3 could be blocked by 800 ng/ml eotaxin, the natural ligand for CCR-3.
Similar articles
- Utilization of chemokine receptors, orphan receptors, and herpesvirus-encoded receptors by diverse human and simian immunodeficiency viruses.
Rucker J, Edinger AL, Sharron M, Samson M, Lee B, Berson JF, Yi Y, Margulies B, Collman RG, Doranz BJ, Parmentier M, Doms RW. Rucker J, et al. J Virol. 1997 Dec;71(12):8999-9007. doi: 10.1128/JVI.71.12.8999-9007.1997. J Virol. 1997. PMID: 9371556 Free PMC article. - CD4-independent infection by human immunodeficiency virus type 2 strain ROD/B: the role of the N-terminal domain of CXCR-4 in fusion and entry.
Potempa S, Picard L, Reeves JD, Wilkinson D, Weiss RA, Talbot SJ. Potempa S, et al. J Virol. 1997 Jun;71(6):4419-24. doi: 10.1128/JVI.71.6.4419-4424.1997. J Virol. 1997. PMID: 9151832 Free PMC article. - Adaptation to promiscuous usage of CC and CXC-chemokine coreceptors in vivo correlates with HIV-1 disease progression.
Xiao L, Rudolph DL, Owen SM, Spira TJ, Lal RB. Xiao L, et al. AIDS. 1998 Sep 10;12(13):F137-43. doi: 10.1097/00002030-199813000-00001. AIDS. 1998. PMID: 9764773 - Unwelcomed guests with master keys: how HIV uses chemokine receptors for cellular entry.
Doms RW, Peiper SC. Doms RW, et al. Virology. 1997 Sep 1;235(2):179-90. doi: 10.1006/viro.1997.8703. Virology. 1997. PMID: 9281497 Review. No abstract available. - Chemokine receptors as fusion cofactors for human immunodeficiency virus type 1 (HIV-1).
Doranz BJ, Berson JF, Rucker J, Doms RW. Doranz BJ, et al. Immunol Res. 1997 Feb;16(1):15-28. doi: 10.1007/BF02786321. Immunol Res. 1997. PMID: 9048206 Review.
Cited by
- Platelet and HIV Interactions and Their Contribution to Non-AIDS Comorbidities.
Awamura T, Nakasone ES, Gangcuangco LM, Subia NT, Bali AJ, Chow DC, Shikuma CM, Park J. Awamura T, et al. Biomolecules. 2023 Nov 2;13(11):1608. doi: 10.3390/biom13111608. Biomolecules. 2023. PMID: 38002289 Free PMC article. Review. - Characterization of Macrophage-Tropic HIV-1 Infection of Central Nervous System Cells and the Influence of Inflammation.
Woodburn BM, Kanchi K, Zhou S, Colaianni N, Joseph SB, Swanstrom R. Woodburn BM, et al. J Virol. 2022 Sep 14;96(17):e0095722. doi: 10.1128/jvi.00957-22. Epub 2022 Aug 17. J Virol. 2022. PMID: 35975998 Free PMC article. - International Union of Basic and Clinical Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors.
Bachelerie F, Ben-Baruch A, Burkhardt AM, Combadiere C, Farber JM, Graham GJ, Horuk R, Sparre-Ulrich AH, Locati M, Luster AD, Mantovani A, Matsushima K, Murphy PM, Nibbs R, Nomiyama H, Power CA, Proudfoot AE, Rosenkilde MM, Rot A, Sozzani S, Thelen M, Yoshie O, Zlotnik A. Bachelerie F, et al. Pharmacol Rev. 2013 Nov 11;66(1):1-79. doi: 10.1124/pr.113.007724. Print 2014. Pharmacol Rev. 2013. PMID: 24218476 Free PMC article. Review. - Susceptibility of HIV type 2 primary isolates to CCR5 and CXCR4 monoclonal antibodies, ligands, and small molecule inhibitors.
Espirito-Santo M, Santos-Costa Q, Calado M, Dorr P, Azevedo-Pereira JM. Espirito-Santo M, et al. AIDS Res Hum Retroviruses. 2012 May;28(5):478-85. doi: 10.1089/AID.2011.0124. Epub 2011 Oct 3. AIDS Res Hum Retroviruses. 2012. PMID: 21902586 Free PMC article. - Host genetic factors in susceptibility to HIV-1 infection and progression to AIDS.
Chatterjee K. Chatterjee K. J Genet. 2010 Apr;89(1):109-16. doi: 10.1007/s12041-010-0003-4. J Genet. 2010. PMID: 20505255 Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Research Materials