Wound infection. A failure of wound healing caused by an imbalance of bacteria - PubMed (original) (raw)
Review
Wound infection. A failure of wound healing caused by an imbalance of bacteria
M C Robson. Surg Clin North Am. 1997 Jun.
Abstract
Infection in a wound, like infection elsewhere in the body, is a manifestation of a disturbed host-bacteria equilibrium in favor of the bacteria. This not only elicits a systemic septic response but actually inhibits the multiple processes involved in the wound healing scheme. Each process involved in healing is affected when bacteria proliferate in a wound. Wound infection, whether in an intentional operative incision, an acute traumatic laceration, or a chronic pressure ulcer, results when bacteria indigenous to the patient or exogenous to the wound achieve dominance over the systemic and local factors of host resistance. To be able to prevent and manage wound infections requires an understanding of how each prophylactic or therapeutic maneuver works to maintain or re-establish the bacteria-host balance. Only when this equilibrium is in balance can the normal processes of wound healing proceed to give a satisfactory healing trajectory.
Similar articles
- Infection in the surgical patient: an imbalance in the normal equilibrium.
Robson MC. Robson MC. Clin Plast Surg. 1979 Oct;6(4):493-503. Clin Plast Surg. 1979. PMID: 391469 - Bacteria and wound healing.
Edwards R, Harding KG. Edwards R, et al. Curr Opin Infect Dis. 2004 Apr;17(2):91-6. doi: 10.1097/00001432-200404000-00004. Curr Opin Infect Dis. 2004. PMID: 15021046 Review. - Immunology, microbiology, and the recalcitrant wound.
Thomson PD. Thomson PD. Ostomy Wound Manage. 2000 Jan;46(1A Suppl):77S-82S; quiz 83S-84S. Ostomy Wound Manage. 2000. PMID: 10732642 Review. - The 10(5) bacterial growth guideline: reassessing its clinical relevance in wound healing.
Bowler PG. Bowler PG. Ostomy Wound Manage. 2003 Jan;49(1):44-53. Ostomy Wound Manage. 2003. PMID: 12532033 Review. - [Surgical infections].
Reith HB, Rauchschwalbe S, Endter F, Thiede A. Reith HB, et al. Zentralbl Chir. 2003 Sep;128(9):W88-96, quiz W97-100. Zentralbl Chir. 2003. PMID: 14569984 Review. German. No abstract available.
Cited by
- Possible healthcare-associated transmission as a cause of secondary infection and population structure of Staphylococcus aureus isolates from two wound treatment centres in Ghana.
Kpeli G, Darko Otchere I, Lamelas A, Buultjens AL, Bulach D, Baines SL, Seemann T, Giulieri S, Nakobu Z, Aboagye SY, Owusu-Mireku E, Pluschke G, Stinear TP, Yeboah-Manu D. Kpeli G, et al. New Microbes New Infect. 2016 Jul 12;13:92-101. doi: 10.1016/j.nmni.2016.07.001. eCollection 2016 Sep. New Microbes New Infect. 2016. PMID: 27547406 Free PMC article. - Wound healing applications of sericin/chitosan-capped silver nanoparticles incorporated hydrogel.
Verma J, Kanoujia J, Parashar P, Tripathi CB, Saraf SA. Verma J, et al. Drug Deliv Transl Res. 2017 Feb;7(1):77-88. doi: 10.1007/s13346-016-0322-y. Drug Deliv Transl Res. 2017. PMID: 27565984 - Clinical and Antibiofilm Efficacy of Antimicrobial Hydrogels.
Finnegan S, Percival SL. Finnegan S, et al. Adv Wound Care (New Rochelle). 2015 Jul 1;4(7):398-406. doi: 10.1089/wound.2014.0556. Adv Wound Care (New Rochelle). 2015. PMID: 26155382 Free PMC article. Review. - Comparison of bacteria-retaining ability of absorbent wound dressings.
Tachi M, Hirabayashi S, Yonehara Y, Suzuki Y, Bowler P. Tachi M, et al. Int Wound J. 2004 Sep;1(3):177-81. doi: 10.1111/j.1742-4801.2004.00058.x. Int Wound J. 2004. PMID: 16722876 Free PMC article. - Development of an experimental model of infected skin ulcer.
Tachi M, Hirabayashi S, Yonehara Y, Suzuki Y, Bowler P. Tachi M, et al. Int Wound J. 2004 Apr;1(1):49-55. doi: 10.1111/j.1742-481x.2004.00006.x. Int Wound J. 2004. PMID: 16722897 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources