Pathways leading to cell death in T cells - PubMed (original) (raw)
Review
Pathways leading to cell death in T cells
B Wong et al. Curr Opin Immunol. 1997 Jun.
Abstract
Antigen-induced apoptosis of T cells is a highly regulated process which plays a key role in the elimination of self-reactive T cells and, thus, in the prevention of autoimmunity. It has recently become apparent that members of the tumor necrosis factor (TNF) and TNF receptor (TNFR) superfamily regulate antigen-induced T-cell death. Studies characterizing genes which control TNF/TNFR superfamily expression and how TNF/TNFR signal transducers activate cell death machinery, such as caspases, have begun to reveal the molecular control of antigen-induced T-cell death.
Similar articles
- Tumor necrosis factor/tumor necrosis factor receptor family members that positively regulate immunity.
So T, Lee SW, Croft M. So T, et al. Int J Hematol. 2006 Jan;83(1):1-11. doi: 10.1532/IJH97.05120. Int J Hematol. 2006. PMID: 16443545 Review. - Apoptosis signaling in lymphocytes.
Scaffidi C, Kirchhoff S, Krammer PH, Peter ME. Scaffidi C, et al. Curr Opin Immunol. 1999 Jun;11(3):277-85. doi: 10.1016/s0952-7915(99)80045-4. Curr Opin Immunol. 1999. PMID: 10375553 Review. - A crucial role for p80 TNF-R2 in amplifying p60 TNF-R1 apoptosis signals in T lymphocytes.
Chan FK, Lenardo MJ. Chan FK, et al. Eur J Immunol. 2000 Feb;30(2):652-60. doi: 10.1002/1521-4141(200002)30:2<652::AID-IMMU652>3.0.CO;2-L. Eur J Immunol. 2000. PMID: 10671223 - Death receptor signaling and autoimmunity.
Siegel RM, Muppidi J, Roberts M, Porter M, Wu Z. Siegel RM, et al. Immunol Res. 2003;27(2-3):499-512. doi: 10.1385/IR:27:2-3:499. Immunol Res. 2003. PMID: 12857993 Review. - Siva-1 and an alternative splice form lacking the death domain, Siva-2, similarly induce apoptosis in T lymphocytes via a caspase-dependent mitochondrial pathway.
Py B, Slomianny C, Auberger P, Petit PX, Benichou S. Py B, et al. J Immunol. 2004 Apr 1;172(7):4008-17. doi: 10.4049/jimmunol.172.7.4008. J Immunol. 2004. PMID: 15034012
Cited by
- Novel Functions of Integrins as Receptors of CD154: Their Role in Inflammation and Apoptosis.
Hassan GS, Salti S, Mourad W. Hassan GS, et al. Cells. 2022 May 25;11(11):1747. doi: 10.3390/cells11111747. Cells. 2022. PMID: 35681441 Free PMC article. Review. - Lymphocyte apoptosis in children with central nervous system tuberculosis: a case control study.
Di Carlo P, Casuccio A, Romano A, Spicola D, Titone L, Caccamo N, Dieli F, Mammina C, Pace E, Gjomarkaj M, Melis M, Tolomeo M. Di Carlo P, et al. BMC Pediatr. 2011 Nov 23;11:108. doi: 10.1186/1471-2431-11-108. BMC Pediatr. 2011. PMID: 22111973 Free PMC article. - Effects of parathyroid hormone-related protein and macrophage inflammatory protein-1α in Jurkat T-cells on tumor formation in vivo and expression of apoptosis regulatory genes in vitro.
Shu ST, Dirksen WP, Lanigan LG, Martin CK, Thudi NK, Werbeck JL, Fernandez SA, Hildreth BE 3rd, Rosol TJ. Shu ST, et al. Leuk Lymphoma. 2012 Apr;53(4):688-98. doi: 10.3109/10428194.2011.626883. Epub 2012 Jan 3. Leuk Lymphoma. 2012. PMID: 21942940 Free PMC article. - Differential expression of immunomodulatory galectin-1 in peripheral leukocytes and adult tissues and its cytosolic organization in striated muscle.
Dias-Baruffi M, Stowell SR, Song SC, Arthur CM, Cho M, Rodrigues LC, Montes MA, Rossi MA, James JA, McEver RP, Cummings RD. Dias-Baruffi M, et al. Glycobiology. 2010 May;20(5):507-20. doi: 10.1093/glycob/cwp203. Epub 2010 Jan 5. Glycobiology. 2010. PMID: 20053628 Free PMC article.