Laboratory investigation of enteroaggregative Escherichia coli O untypeable:H10 associated with a massive outbreak of gastrointestinal illness - PubMed (original) (raw)
Laboratory investigation of enteroaggregative Escherichia coli O untypeable:H10 associated with a massive outbreak of gastrointestinal illness
Y Itoh et al. J Clin Microbiol. 1997 Oct.
Abstract
A massive outbreak of gastrointestinal illness occurred in Tajimi city, Gifu prefecture, in June of 1993 in which 2,697 children in elementary and junior high schools developed severe diarrhea. Stool specimens from 30 children with severe protracted diarrhea were studied. Twenty-seven strains of enteroaggregative Escherichia coli (EAggEC) isolated from 12 of 30 patients all belonged to the same serotype, O untypeable (OUT):H10, and showed the same biochemical characteristics and antibiotic susceptibility pattern. These strains were negative for the virulence factors of the four standard categories of diarrheagenic E. coli (enterotoxigenic, enteropathogenic, enteroinvasive, and enterohemorrhagic). However, the isolates showed an aggregative pattern of adherence to HEp-2 cells and had a 60-MDa plasmid and an astA gene, which encodes heat-stable enterotoxin-1 production. These data suggested that the EAggEC serotype OUT:H10 was associated with this massive outbreak of gastrointestinal illness.
Similar articles
- Diarrheagenic Escherichia coli isolated from stools of sporadic cases of diarrheal illness in Osaka City, Japan between 1997 and 2000: prevalence of enteroaggregative E. coli heat-stable enterotoxin 1 gene-possessing E. coli.
Nishikawa Y, Zhou Z, Hase A, Ogasawara J, Kitase T, Abe N, Nakamura H, Wada T, Ishii E, Haruki K; Surveillance Team. Nishikawa Y, et al. Jpn J Infect Dis. 2002 Dec;55(6):183-90. Jpn J Infect Dis. 2002. PMID: 12606826 - Characterization of atypical enteropathogenic Escherichia coli strains harboring the astA gene that were associated with a waterborne outbreak of diarrhea in Japan.
Yatsuyanagi J, Saito S, Miyajima Y, Amano K, Enomoto K. Yatsuyanagi J, et al. J Clin Microbiol. 2003 May;41(5):2033-9. doi: 10.1128/JCM.41.5.2033-2039.2003. J Clin Microbiol. 2003. PMID: 12734245 Free PMC article. - [Characteristics of enterotoxigenic Escherichia coli and E. coli harboring enteroaggregative E. coli heat-stable enterotoxin-1 (EAST-1) gene isolated from a water-borne outbreak].
Yatsuyanagi J, Saito S, Kinouchi Y, Sato H, Morita M, Itoh K. Yatsuyanagi J, et al. Kansenshogaku Zasshi. 1996 Mar;70(3):215-23. doi: 10.11150/kansenshogakuzasshi1970.70.215. Kansenshogaku Zasshi. 1996. PMID: 8621962 Japanese. - Enteroaggregative Escherichia coli.
Law D, Chart H. Law D, et al. J Appl Microbiol. 1998 May;84(5):685-97. doi: 10.1046/j.1365-2672.1998.00372.x. J Appl Microbiol. 1998. PMID: 9674119 Review. - Escherichia coli that cause diarrhea: enterotoxigenic, enteropathogenic, enteroinvasive, enterohemorrhagic, and enteroadherent.
Levine MM. Levine MM. J Infect Dis. 1987 Mar;155(3):377-89. doi: 10.1093/infdis/155.3.377. J Infect Dis. 1987. PMID: 3543152 Review.
Cited by
- Enteroaggregative Escherichia coli in mid-Norway: A prospective, case control study.
Haugan I, Husby MG, Skjøtskift B, Aamnes Mostue D, Brun A, Olsen LC, Simpson MR, Lange H, Afset JE. Haugan I, et al. PLoS One. 2024 Apr 18;19(4):e0301625. doi: 10.1371/journal.pone.0301625. eCollection 2024. PLoS One. 2024. PMID: 38635516 Free PMC article. - Transposon mutagenesis of atypical enteroaggregative Escherichia coli reveals a hemagglutinin-associated protein that mediates cell adhesion and contributes to the Galleria mellonella virulence.
Monfardini MV, Souza RT, Rojas TCG, Guerrieri CG, Orikaza C, Scaletsky ICA. Monfardini MV, et al. Front Cell Infect Microbiol. 2023 Jun 23;13:1166158. doi: 10.3389/fcimb.2023.1166158. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37424788 Free PMC article. - Enteroaggregative Escherichia coli as etiological agent of endemic diarrhea in Spain: A prospective multicenter prevalence study with molecular characterization of isolates.
Llorente MT, Escudero R, Ramiro R, Remacha MA, Martínez-Ruiz R, Galán-Sánchez F, de Frutos M, Elía M, Onrubia I, Sánchez S. Llorente MT, et al. Front Microbiol. 2023 Mar 20;14:1120285. doi: 10.3389/fmicb.2023.1120285. eCollection 2023. Front Microbiol. 2023. PMID: 37065134 Free PMC article. - High Burden of Co-Infection with Multiple Enteric Pathogens in Children Suffering with Diarrhoea from Rural and Peri-Urban Communities in South Africa.
Potgieter N, Heine L, Ngandu JPK, Ledwaba SE, Zitha T, Mudau LS, Becker P, Traore AN, Barnard TG. Potgieter N, et al. Pathogens. 2023 Feb 14;12(2):315. doi: 10.3390/pathogens12020315. Pathogens. 2023. PMID: 36839587 Free PMC article. - Adhesin related genes as potential markers for the enteroaggregative Escherichia coli category.
Freire CA, Rodrigues BO, Elias WP, Abe CM. Freire CA, et al. Front Cell Infect Microbiol. 2022 Nov 8;12:997208. doi: 10.3389/fcimb.2022.997208. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 36425788 Free PMC article.
References
- J Bacteriol. 1994 Aug;176(16):4949-57 - PubMed
- Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):3093-7 - PubMed
- J Clin Microbiol. 1995 Mar;33(3):701-5 - PubMed
- J Clin Microbiol. 1995 May;33(5):1414-7 - PubMed
- Infect Immun. 1973 Nov;8(5):725-30 - PubMed
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical