KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene - PubMed (original) (raw)

T F Burns, E R McDonald 3rd, W Jiang, R Meng, I D Krantz, G Kao, D D Gan, J Y Zhou, R Muschel, S R Hamilton, N B Spinner, S Markowitz, G Wu, W S el-Deiry

• PMID: 9326928
• DOI: 10.1038/ng1097-141

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

G S Wu et al. Nat Genet. 1997 Oct.

No abstract available

PubMed Disclaimer

Similar articles

• Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site.
  Takimoto R, El-Deiry WS. Takimoto R, et al. Oncogene. 2000 Mar 30;19(14):1735-43. doi: 10.1038/sj.onc.1203489. Oncogene. 2000. PMID: 10777207
• Rare loss-of-function mutation of a death receptor gene in head and neck cancer.
  Pai SI, Wu GS, Ozören N, Wu L, Jen J, Sidransky D, El-Deiry WS. Pai SI, et al. Cancer Res. 1998 Aug 15;58(16):3513-8. Cancer Res. 1998. PMID: 9721851
• Evidence that the death receptor DR4 is a DNA damage-inducible, p53-regulated gene.
  Guan B, Yue P, Clayman GL, Sun SY. Guan B, et al. J Cell Physiol. 2001 Jul;188(1):98-105. doi: 10.1002/jcp.1101. J Cell Physiol. 2001. PMID: 11382926
• Poxvirus-encoded soluble cytokine receptors.
  Spriggs MK. Spriggs MK. Virus Res. 1994 Jul;33(1):1-10. doi: 10.1016/0168-1702(94)90013-2. Virus Res. 1994. PMID: 7941696 Review. No abstract available.

Cited by

• Ninjurin 2, a Cell Adhesion Molecule and a Target of p53, Modulates Wild-Type p53 in Growth Suppression and Mutant p53 in Growth Promotion.
  Zhang J, Kong X, Yang HJ, Mohibi S, Lucchesi CA, Zhang W, Chen X. Zhang J, et al. Cancers (Basel). 2024 Jan 4;16(1):229. doi: 10.3390/cancers16010229. Cancers (Basel). 2024. PMID: 38201656 Free PMC article.
• ONC201/TIC10 plus TLY012 anti-cancer effects via apoptosis inhibitor downregulation, stimulation of integrated stress response and death receptor DR5 in gastric adenocarcinoma.
  Parker CS, Zhou L, Prabhu VV, Lee S, Miner TJ, Ross EA, El-Deiry WS. Parker CS, et al. Am J Cancer Res. 2023 Dec 15;13(12):6290-6312. eCollection 2023. Am J Cancer Res. 2023. PMID: 38187068 Free PMC article.
• PUMA/RIP3 Mediates Chemotherapy Response via Necroptosis and Local Immune Activation in Colorectal Cancer.
  Chen D, Ermine K, Wang YJ, Chen X, Lu X, Wang P, Beer-Stolz D, Yu J, Zhang L. Chen D, et al. Mol Cancer Ther. 2024 Mar 4;23(3):354-367. doi: 10.1158/1535-7163.MCT-23-0162. Mol Cancer Ther. 2024. PMID: 37992761 Free PMC article.
• Mechanisms of UV-induced human lymphocyte apoptosis.
  Nakvasina MA, Holyavka MG, Artyukhov VG, Radchenko MS, Lidokhova OV. Nakvasina MA, et al. Biophys Rev. 2023 Sep 14;15(5):1257-1267. doi: 10.1007/s12551-023-01142-w. eCollection 2023 Oct. Biophys Rev. 2023. PMID: 37974997 Free PMC article. Review.
• The role of the immune response and inflammatory pathways in TNF-related apoptosis-inducing ligand (TRAIL) resistance in triple-negative breast cancer cells.
  Pimentel JM, Zhou JY, Kim S, Gurdziel K, Wu GS. Pimentel JM, et al. Am J Cancer Res. 2023 Oct 15;13(10):4678-4692. eCollection 2023. Am J Cancer Res. 2023. PMID: 37970367 Free PMC article.

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Nature Publishing Group

• Other Literature Sources

  • The Lens - Patent Citations

• Molecular Biology Databases

  • BioCyc
  • GlyGen glycoinformatics resource

• Research Materials

  • NCI CPTC Antibody Characterization Program

• Miscellaneous

  • NCI CPTAC Assay Portal