The role of calcium in the regulation of apoptosis - PubMed (original) (raw)
Review
. 1997 Oct 20;239(2):357-66.
doi: 10.1006/bbrc.1997.7409.
Affiliations
- PMID: 9344835
- DOI: 10.1006/bbrc.1997.7409
Review
The role of calcium in the regulation of apoptosis
D J McConkey et al. Biochem Biophys Res Commun. 1997.
Abstract
Apoptosis (programmed cell death) has gained widespread attention due to its roles in a variety of physiological and pathological processes, yet precisely how apoptosis is regulated by external and internal cues remains unclear. Work from our laboratories and others has implicated alterations in intracellular Ca2+ in apoptosis, and more recent work has defined particular biochemical processes that are targeted by Ca2+ in apoptotic cells. This review will summarize the role of Ca2+ in apoptosis within the context of what is known about the core components of the effector machinery for apoptosis.
Copyright 1997 Academic Press.
Similar articles
- The role of calcium in the regulation of apoptosis.
McConkey DJ, Orrenius S. McConkey DJ, et al. J Leukoc Biol. 1996 Jun;59(6):775-83. J Leukoc Biol. 1996. PMID: 8691060 Review. - The role of calcium in the regulation of apoptosis.
McConkey DJ. McConkey DJ. Scanning Microsc. 1996;10(3):777-93; discussion 793-4. Scanning Microsc. 1996. PMID: 9813639 Review. - Physician Education: Apoptosis.
Kataoka S, Tsuruo T. Kataoka S, et al. Oncologist. 1996;1(6):399-401. Oncologist. 1996. PMID: 10388021 - Importance of the role of calcium in programmed cell death: a review.
Gupta PD, Pushkala K. Gupta PD, et al. Cytobios. 1999;99(391):83-95. Cytobios. 1999. PMID: 10582325 Review. - Regulation of cell death: the calcium-apoptosis link.
Orrenius S, Zhivotovsky B, Nicotera P. Orrenius S, et al. Nat Rev Mol Cell Biol. 2003 Jul;4(7):552-65. doi: 10.1038/nrm1150. Nat Rev Mol Cell Biol. 2003. PMID: 12838338 Review.
Cited by
- Therapeutic Potential of Intermittent Hypoxia in Atrial Fibrillation.
Park H, Park B, Kim KS, Son YH, Park SJ, Lee K, Park H, Park J. Park H, et al. Int J Mol Sci. 2024 Oct 15;25(20):11085. doi: 10.3390/ijms252011085. Int J Mol Sci. 2024. PMID: 39456866 Free PMC article. - The Impact of Enteral Nimodipine on Endothelial Cell Apoptosis in an Animal Subarachnoid Hemorrhage Model.
Cho YD, Byoun HS, Park KH, Won YI, Lim J. Cho YD, et al. Neurocrit Care. 2024 Oct;41(2):608-618. doi: 10.1007/s12028-024-01980-w. Epub 2024 Apr 8. Neurocrit Care. 2024. PMID: 38589694 - Calcium signals and potential therapy targets in ovarian cancer (Review).
Deng F, Fu M, Zhao C, Lei J, Xu T, Ji B, Ding H, Zhang Y, Chen J, Qiu J, Gao Q. Deng F, et al. Int J Oncol. 2023 Nov;63(5):125. doi: 10.3892/ijo.2023.5573. Epub 2023 Sep 15. Int J Oncol. 2023. PMID: 37711071 Free PMC article. Review. - A Dominant-Negative Mutant of ANXA7 Impairs Calcium Signaling and Enhances the Proliferation of Prostate Cancer Cells by Downregulating the IP3 Receptor and the PI3K/mTOR Pathway.
Srivastava M, Bera A, Eidelman O, Tran MB, Jozwik C, Glasman M, Leighton X, Caohuy H, Pollard HB. Srivastava M, et al. Int J Mol Sci. 2023 May 16;24(10):8818. doi: 10.3390/ijms24108818. Int J Mol Sci. 2023. PMID: 37240163 Free PMC article. - Nitric Oxide/Nitric Oxide Synthase System in the Pathogenesis of Neurodegenerative Disorders-An Overview.
Iova OM, Marin GE, Lazar I, Stanescu I, Dogaru G, Nicula CA, Bulboacă AE. Iova OM, et al. Antioxidants (Basel). 2023 Mar 20;12(3):753. doi: 10.3390/antiox12030753. Antioxidants (Basel). 2023. PMID: 36979000 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Miscellaneous