Replication of murine coronaviruses in mouse embryonic stem cell lines in vitro - PubMed (original) (raw)

Replication of murine coronaviruses in mouse embryonic stem cell lines in vitro

S Kyuwa. Exp Anim. 1997 Oct.

Free article

Abstract

Replication of murine coronaviruses in eight mouse embryonic stem (ES) cell lines of several genetic backgrounds was examined. Both mouse hepatitis virus (MHV) type 2 and MHV, strain A59 replicated well with no or minimal cytopathic effect in all the ES cell lines tested. The results suggest the possibility that MHV-infected ES cells may disseminate MHV in mouse colonies due to embryo manipulation.

PubMed Disclaimer

Similar articles

• Maintenance of pluripotency in mouse embryonic stem cells persistently infected with murine coronavirus.
  Okumura A, Machii K, Azuma S, Toyoda Y, Kyuwa S. Okumura A, et al. J Virol. 1996 Jun;70(6):4146-9. doi: 10.1128/JVI.70.6.4146-4149.1996. J Virol. 1996. PMID: 8648758 Free PMC article.
• The N-terminal region of the murine coronavirus spike glycoprotein is associated with the extended host range of viruses from persistently infected murine cells.
  Schickli JH, Thackray LB, Sawicki SG, Holmes KV. Schickli JH, et al. J Virol. 2004 Sep;78(17):9073-83. doi: 10.1128/JVI.78.17.9073-9083.2004. J Virol. 2004. PMID: 15308703 Free PMC article.
• Mouse hepatitis virus strain A59 is released from opposite sides of different epithelial cell types.
  Rossen JW, Strous GJ, Horzinek MC, Rottier PJ. Rossen JW, et al. J Gen Virol. 1997 Jan;78 ( Pt 1):61-9. doi: 10.1099/0022-1317-78-1-61. J Gen Virol. 1997. PMID: 9010286
• The cellular and molecular pathogenesis of coronaviruses.
  Compton SR, Barthold SW, Smith AL. Compton SR, et al. Lab Anim Sci. 1993 Feb;43(1):15-28. Lab Anim Sci. 1993. PMID: 8384676 Review.
• [Mouse hepatitis virus].
  Homberger FR. Homberger FR. Schweiz Arch Tierheilkd. 1996;138(4):183-8. Schweiz Arch Tierheilkd. 1996. PMID: 8677422 Review. German.

Cited by

• Basic reproduction numbers of three strains of mouse hepatitis viruses in mice.
  Nakayama M, Kyuwa S. Nakayama M, et al. Microbiol Immunol. 2022 Apr;66(4):166-172. doi: 10.1111/1348-0421.12961. Epub 2022 Jan 18. Microbiol Immunol. 2022. PMID: 34984727 Free PMC article.
• Impairment of germline transmission after blastocyst injection with murine embryonic stem cells cultured with mouse hepatitis virus and mouse minute virus.
  Mahabir E, Reindl K, Mysliwietz J, Needham J, Bulian D, Markoullis K, Scherb H, Schmidt J. Mahabir E, et al. Transgenic Res. 2009 Feb;18(1):45-57. doi: 10.1007/s11248-008-9216-1. Epub 2008 Sep 18. Transgenic Res. 2009. PMID: 18800235 Free PMC article.
• Rodent and germplasm trafficking: risks of microbial contamination in a high-tech biomedical world.
  Mahabir E, Bauer B, Schmidt J. Mahabir E, et al. ILAR J. 2008;49(3):347-355. doi: 10.1093/ilar.49.3.347. ILAR J. 2008. PMID: 18506068 Free PMC article.
• From bench to cageside: Risk assessment for rodent pathogen contamination of cells and biologics.
  Peterson NC. Peterson NC. ILAR J. 2008;49(3):310-5. doi: 10.1093/ilar.49.3.310. ILAR J. 2008. PMID: 18506064 Free PMC article. Review.
• Coronavirus replication complex formation utilizes components of cellular autophagy.
  Prentice E, Jerome WG, Yoshimori T, Mizushima N, Denison MR. Prentice E, et al. J Biol Chem. 2004 Mar 12;279(11):10136-41. doi: 10.1074/jbc.M306124200. Epub 2003 Dec 29. J Biol Chem. 2004. PMID: 14699140 Free PMC article.

MeSH terms

LinkOut - more resources

• Full Text Sources

  • J-STAGE, Japan Science and Technology Information Aggregator, Electronic

• Research Materials

  • Cellosaurus - a cell line knowledge resource